Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | MAOA | P21397 | 3/20 | 0.64 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.64 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.62 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | DPP4 | P27487 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5606932 | 0.91 | ABCG2 (0.78) | ABCG2MAPTMAOACHRNA7CXCL12 | |
| SCHEMBL14837108 | 0.91 | ABCG2 (0.78) | ABCG2MAPTMAOACHRNA7CXCL12 | |
| SCHEMBL14836729 | 0.91 | ABCG2 (0.78) | ABCG2MAPTMAOACHRNA7CXCL12 | |
| SCHEMBL28400854 | 0.87 | ABCG2 (0.72) | ABCG2LMNAMAPTMAOACHRNA7 | |
| SCHEMBL14837404 | 0.87 | ABCG2 (0.72) | ABCG2LMNAMAPTMAOACHRNA7 | |
| SCHEMBL4160326 | 0.85 | ABCG2 (0.68) | ABCG2MAPTHPGDMAOACHRNA7 | |
| SCHEMBL15155210 | 0.82 | ABCG2 (0.94) | ABCG2LMNAMAPTHPGDMAOA | |
| SCHEMBL15155219 | 0.82 | ABCG2 (0.94) | ABCG2LMNAMAPTHPGDMAOA | |
| SCHEMBL28695326 | 0.81 | CTSL (0.66) | ABCG2MAOACHRNA7MAOBDPP4 | |
| SCHEMBL28695325 | 0.81 | CTSL (0.66) | ABCG2MAOACHRNA7MAOBDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781305-A2 | COMPOSITIONS AND METHODS USING HYALURONIC ACID AND HYALURONIDASE INHIBITORS | ANGIOTECH INTERNATIONAL AG (CH) | 2007-05-09 | — | — | EP | claimed |
| WO-2006020994-A2 | COMPOSITIONS AND METHODS USING HYALURONIC ACID AND HYLURONIDASE INHIBITORS | ANGIOTECH INTERNATIONAL AG (CH) | 2006-02-23 | — | — | WO | claimed |
| EP-1781305-A2 | COMPOSITIONS AND METHODS USING HYALURONIC ACID AND HYALURONIDASE INHIBITORS | ANGIOTECH INTERNATIONAL AG (CH) | 2007-05-09 | — | — | EP | disclosed |
| US-20060040894-A1 | Compositions and methods using hyaluronic acid | ANGIOTECH INTERNATIONAL AG (CH) | 2006-02-23 | — | — | US | disclosed |
| WO-2006020994-A2 | COMPOSITIONS AND METHODS USING HYALURONIC ACID AND HYLURONIDASE INHIBITORS | ANGIOTECH INTERNATIONAL AG (CH) | 2006-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040894-A1 | Compositions and methods using hyaluronic acid | CD44, MMP13, MMP1 | ABCG2 508/4885LMNA 1184/4885MAPT 4556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.