SCHEMBL1483698

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1483382	0.90	MAPT (0.44)	MAPTCYP2C9CYP2C19MEN1NPC1
	SCHEMBL1484311	0.86	EGFR (0.40)	MAPTCYP2C9CYP2C19MEN1NPC1
	SCHEMBL1483351	0.83	EGFR (0.38)	MAPTCYP2C9CYP2C19MEN1NPC1
	SCHEMBL1483371	0.81	TEAD2 (0.44)	MAPTNPC1RAB9ASMN1; SMN2MAOB
	SCHEMBL1483741	0.81	THRB (0.47)	MAPTCYP2C9CYP2C19MEN1NPC1
	SCHEMBL1483247	0.80	MAPT (0.48)	MAPTCYP2C9CYP2C19MEN1GAA
	SCHEMBL27653649	0.78	KDM4E (0.47)	MAPTCYP2C9CYP2C19MEN1NPC1
	SCHEMBL1482972	0.76	EGFR (0.39)	MAPTMEN1NPC1RAB9AKMT2A
	SCHEMBL1483213	0.75	PTPN1 (0.38)	MAPTKMT2ATP53POLBALDH1A1
	SCHEMBL1484308	0.75	EGFR (0.36)	MAPTMEN1NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.