SCHEMBL14838014

SCHEMBL14838014

O=C1C=C(CO)C(=O)C=C1O

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
XIAP P98170 1/20 0.34
PIM1 P11309 2/20 0.33
ERBB2 P04626 1/20 0.33
HKDC1 Q2TB90 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
PTPN22 Q9Y2R2 1/20 0.32
STAT3 P40763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28875633 0.78 KDM4E (0.43) XIAPKDM4EALDH1A1CYP3A4MAPT
Potassium SCHEMBL29990441 0.74 KDM4E (0.42) XIAPKDM4EALDH1A1CYP3A4MAPT
SCHEMBL28391346 0.74 KDM4E (0.42) XIAPPIM1ERBB2HKDC1KDM4E
SCHEMBL11135771 0.74 KDM4E (0.42) XIAPKDM4EALDH1A1CYP3A4MAPT
SCHEMBL28758922 0.74 KDM4E (0.42) XIAPKDM4EALDH1A1CYP3A4MAPT
SCHEMBL28480828 0.74 KDM4E (0.47) XIAPKDM4EALDH1A1CYP3A4MAPT
Lithium SCHEMBL30194867 0.74 KDM4E (0.42) XIAPKDM4EALDH1A1CYP3A4MAPT
SCHEMBL3968141 0.73 STAT3 (0.59) KDM4EALDH1A1CYP3A4MAPTHPGD
Tetroquinone SCHEMBL28777993 0.69 KDM4E (0.60) XIAPKDM4EALDH1A1CYP3A4MAPT
SCHEMBL5145016 0.67 MAOA (0.48) PIM1ERBB2HKDC1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014154957-A1 DYEING METHOD USING A HAIR-DYEING PRECURSOR OBTAINED FROM IRIDOIDS, COMPOSITION, PRECURSOR AND DEVICE INCLUDING SAME L'OREAL (FR) 2014-10-02 WO disclosed
WO-2013045702-A2 DYE COMPOSITION COMPRISING A NON-GLYCOSYL IRIDOID COMPOUND AND A SPECIFIC NUCLEOPHILE OR AN AMINO OR THIO POLYMER, DYEING PROCESS, AND DEVICE THEREFOR L'OREAL (FR) 2013-04-04 WO disclosed
WO-2013045701-A2 DYEING PROCESS USING A COMPOSITION COMPRISING A GLYCOSYL IRIDOID COMPOUND AND A NUCLEOPHILE OR AN AMINO OR THIO POLYMER, COMPOSITION AND DEVICES THEREFOR L'OREAL (FR) 2013-04-04 WO disclosed