SCHEMBL14838464

SCHEMBL14838464

COc1ccc2cc(-c3ccc(OC)c(O)c3)oc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.61
CYP1A1 P04798 3/20 0.57
CYP1B1 Q16678 3/20 0.57
PTGES O14684 2/20 0.55
AURKA O14965 1/20 0.55
KDR P35968 1/20 0.55
FLT3 P36888 1/20 0.55
AURKB Q96GD4 1/20 0.55
CSNK2A2 P19784 2/20 0.54
CSNK2B P67870 2/20 0.54
CSNK2A1 P68400 2/20 0.54
XDH P47989 2/20 0.54
ABCC1 P33527 2/20 0.54
HDAC6 Q9UBN7 2/20 0.54
KDM1A O60341 1/20 0.54
CYP1A2 P05177 1/20 0.54
IPMK Q8NFU5 1/20 0.54
IP6K2 Q9UHH9 1/20 0.54
CALCRL Q16602 1/20 0.53
APP P05067 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16011311 0.87 ABCB1 (0.66) PTPN1CYP1A1CYP1B1CSNK2A2CSNK2B
SCHEMBL29873464 0.81 APP (0.64) PTPN1APPCA12CA1AKR1B1
SCHEMBL6748778 0.81 APP (0.64) PTPN1APPCA12CA1AKR1B1
SCHEMBL29435863 0.81 CSNK2A2 (0.81) CYP1A1CYP1B1AURKAKDRFLT3
SCHEMBL26117897 0.81 CSNK2A2 (0.81) CYP1A1CYP1B1AURKAKDRFLT3
SCHEMBL20147031 0.78 CALCRL (0.74) PTPN1CYP1A1CYP1B1CSNK2A2CSNK2B
SCHEMBL7117562 0.77 MAOB (0.66) PTPN1APPCA12CA1AKR1B1
SCHEMBL734502 0.76 MAOB (0.65) PTPN1APPCA12CA1AKR1B1
SCHEMBL20473173 0.76 MAOB (0.58) PTPN1HDAC6APPCA12CA1
SCHEMBL734884 0.76 MAOB (0.65) PTPN1APPCA12CA1AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013044371-A1 PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS SWITCH MATERIALS, INC. (CA) 2013-04-04 WO disclosed