SCHEMBL14839422

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15688182	0.80	LRRK2 (0.44)	ALDH1A1LMNALRRK2MAPK1PIK3CA
	SCHEMBL355054	0.80	ALDH1A1 (0.50)	ALDH1A1LMNAMAPK1RXFP1FDPS
	SCHEMBL2657070	0.78	HPGDS (0.45)	ALDH1A1LRRK2MAPK1PIK3CAMAPK8
	SCHEMBL14839431	0.77	ALDH1A1 (0.41)	ALDH1A1LMNACYP1A2CYP2C19MAPK1
	SCHEMBL3091753	0.75	MAPK1 (0.48)	LRRK2MAPK1PIK3CAMAPK8MAPK9
	SCHEMBL2657982	0.73	CYP19A1 (0.47)	ALDH1A1LMNALRRK2MAPK1PIK3CA
	SCHEMBL15688438	0.72	KMT2A (0.50)	ALDH1A1LMNALRRK2MAPK10GCK
	SCHEMBL181171	0.72	LRRK2 (0.40)	ALDH1A1LMNALRRK2MAPK1PIK3CA
	SCHEMBL2669643	0.72	CYP19A1 (0.40)	LRRK2MAPK1PIK3CAMAPK8MAPK9
	SCHEMBL2657999	0.72	MAPK1 (0.38)	LRRK2MAPK1PIK3CAMAPK8MAPK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.