SCHEMBL14840850

SCHEMBL14840850

CN(C)c1ccc2c(-c3ccc(OCCCCC(=O)O)cc3)c3ccc(=[N+](C)C)cc-3oc2c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.64
▸ THRB P10828 1/20 0.64
▸ RECQL P46063 1/20 0.64
▸ BLM P54132 1/20 0.64
▸ KMT2A Q03164 1/20 0.64
▸ TDP1 Q9NUW8 1/20 0.64
▸ CA12 O43570 2/20 0.53
▸ CA1 P00915 2/20 0.53
▸ CA2 P00918 2/20 0.53
▸ CA9 Q16790 2/20 0.53
▸ P2RY6 Q15077 1/20 0.48
▸ SLC5A2 P31639 1/20 0.47
▸ ALDH2 P05091 1/20 0.46
▸ MAOA P21397 1/20 0.46
▸ MAOB P27338 1/20 0.46
▸ ITPR1 Q14643 1/20 0.44
▸ HRH3 Q9Y5N1 1/20 0.43
▸ APAF1 O14727 1/20 0.42
▸ USP2 O75604 1/20 0.42
▸ RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14840738 0.90 MEN1 (0.68) MEN1THRBRECQLBLMKMT2A
SCHEMBL14852999 0.85 MEN1 (0.53) MEN1THRBRECQLBLMKMT2A
SCHEMBL14852996 0.83 MEN1 (0.68) MEN1THRBRECQLBLMKMT2A
SCHEMBL14013320 0.80 MEN1 (0.52) MEN1THRBRECQLBLMKMT2A
SCHEMBL13525202 0.79 MEN1 (1.00) MEN1THRBRECQLBLMKMT2A
SCHEMBL14853113 0.79 MEN1 (0.55) MEN1THRBRECQLBLMKMT2A
Hydrochloric Acid SCHEMBL16295013 0.78 MEN1 (0.98) MEN1THRBRECQLBLMKMT2A
SCHEMBL31716158 0.78 MEN1 (0.54) MEN1THRBRECQLBLMKMT2A
SCHEMBL9350134 0.78 MEN1 (0.54) MEN1THRBRECQLBLMKMT2A
SCHEMBL13524213 0.78 MEN1 (0.75) MEN1THRBRECQLBLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11939350-B2 Fluorescent dyes and methods of use thereof ENZO LIFE SCIENCES, INC. (US) 2024-03-26 — — US disclosed
US-20210079034-A1 FLUORESCENT DYES AND METHODS OF USE THEREOF ENZO LIFE SCIENCES, INC. (US) 2021-03-18 — — US disclosed
US-20210079034-A1 FLUORESCENT DYES AND METHODS OF USE THEREOF ENZO LIFE SCIENCES, INC. (US) 2021-03-18 — — US disclosed
US-10875886-B2 Fluorescent dyes and methods of use thereof ENZO LIFE SCIENCES, INC. (US) 2020-12-29 — — US disclosed
US-10875886-B2 Fluorescent dyes and methods of use thereof ENZO LIFE SCIENCES, INC. (US) 2020-12-29 — — US disclosed
EP-3747877-A1 FLUORESCENT DYES Enzo Life Sciences, Inc., c/o Enzo Biochem, Inc. (US) 2020-12-09 — — EP disclosed
EP-2768306-B1 FLUORESCENT DYES ENZO LIFE SCIENCES INC (US) 2020-07-01 — — EP disclosed
US-20190002491-A1 FLUORESCENT DYES AND METHODS OF USE THEREOF ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) 2019-01-03 — — US disclosed
US-20190002491-A1 FLUORESCENT DYES AND METHODS OF USE THEREOF ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) 2019-01-03 — — US disclosed
US-10106573-B2 Fluorescent dyes and methods of use thereof ENZO LIFE SCIENCES, INC. (US) 2018-10-23 — — US disclosed
US-20160311846-A1 FLUORESCENT DYES AND METHODS OF USE THEREOF ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) 2016-10-27 — — US disclosed
US-9416153-B2 Fluorescent dyes ENZO LIFE SCIENCES, INC. (US) 2016-08-16 — — US disclosed
EP-2768306-A1 FLUORESCENT DYES Enzo Life Sciences, Inc., c/o Enzo Biochem, Inc. (US) 2014-08-27 — — EP disclosed
WO-2013055647-A1 FLUORESCENT DYES ENZO LIFE SCIENCES, INC. (US) 2013-04-18 — — WO disclosed
WO-2013055647-A1 FLUORESCENT DYES ENZO LIFE SCIENCES, INC. (US) 2013-04-18 — — WO disclosed
US-20130089853-A1 FLUORESCENT DYES ENZO LIFE SCIENCES, INC., C/O ENZO BIOCHEM, INC. (US) 2013-04-11 — — US disclosed
US-20130089853-A1 FLUORESCENT DYES ENZO LIFE SCIENCES, INC., C/O ENZO BIOCHEM, INC. (US) 2013-04-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160311846-A1 FLUORESCENT DYES AND METHODS OF USE THEREOF BCDIN3D, EFTUD2, IK MEN1 3646/4885THRB 4416/4885RECQL 1070/4885
US-20210079034-A1 FLUORESCENT DYES AND METHODS OF USE THEREOF BCDIN3D, EFTUD2, IK MEN1 3646/4885THRB 4416/4885RECQL 1070/4885
US-10106573-B2 Fluorescent dyes and methods of use thereof BCDIN3D, EFTUD2, IK MEN1 3646/4885THRB 4416/4885RECQL 1070/4885
US-20130089853-A1 FLUORESCENT DYES KIT, TKFC, IK MEN1 4358/4885THRB 3185/4885RECQL 1043/4885
US-10875886-B2 Fluorescent dyes and methods of use thereof BCDIN3D, EFTUD2, IK MEN1 3646/4885THRB 4416/4885RECQL 1070/4885
US-20190002491-A1 FLUORESCENT DYES AND METHODS OF USE THEREOF BCDIN3D, EFTUD2, IK MEN1 3646/4885THRB 4416/4885RECQL 1070/4885
US-11939350-B2 Fluorescent dyes and methods of use thereof BCDIN3D, EFTUD2, IK MEN1 3646/4885THRB 4416/4885RECQL 1070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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