Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | PRKCB | P05771 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PRKCH | P24723 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17598958 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAAKT1ESR1ADORA3 | |
| SCHEMBL28128353 | 0.77 | — | — | |
| SCHEMBL14233604 | 0.72 | — | — | |
| SCHEMBL4535983 | 0.71 | — | — | |
| SCHEMBL21893376 | 0.69 | — | — | |
| Choline SCHEMBL14841017 | 0.69 | MEN1 (0.38) | SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL2990037 | 0.67 | — | — | |
| SCHEMBL19979301 | 0.67 | LMNA (0.57) | SMN1; SMN2LMNAAKT1ESR1ADORA3 | |
| SCHEMBL3979906 | 0.67 | PPARD (0.42) | — | |
| SCHEMBL21943993 | 0.67 | LMNA (0.49) | SMN1; SMN2LMNAAKT1ESR1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130089912-A1 | METHODS AND COMPOSITIONS FOR THE STABILIZATION OF BIOLOGIC MATERIAL | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE | 2013-04-11 | — | — | US | disclosed |