Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 4/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | FPR3 | P25089 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14842247 | 0.89 | FASN (0.38) | FASNSIGMAR1OPRM1KCNH2 | |
| SCHEMBL14842036 | 0.86 | FASN (0.36) | FASN | |
| SCHEMBL14841999 | 0.86 | OPRM1 (0.45) | FASNSIGMAR1OPRM1FPR3FPR2 | |
| SCHEMBL15582351 | 0.85 | FASN (0.45) | FASNSIGMAR1OPRM1KCNH2MGLL | |
| SCHEMBL15543618 | 0.85 | FASN (0.40) | FASNSIGMAR1OPRM1KCNH2 | |
| SCHEMBL15582388 | 0.84 | SIGMAR1 (0.42) | FASNSIGMAR1OPRM1KCNH2 | |
| SCHEMBL15543738 | 0.83 | — | — | |
| SCHEMBL15556993 | 0.83 | FASN (0.36) | FASNSIGMAR1OPRM1KCNH2 | |
| SCHEMBL15582350 | 0.83 | FASN (0.39) | FASNSIGMAR1OPRM1KCNH2MGLL | |
| SCHEMBL15581812 | 0.82 | FASN (0.42) | FASNSIGMAR1OPRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014008223-A2 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2014-01-09 | — | — | WO | disclosed |
| WO-2013052716-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-04-11 | — | — | WO | disclosed |