⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21184103 | 0.73 | — | — | |
| SCHEMBL264678 | 0.73 | — | — | |
| SCHEMBL9852536 | 0.73 | TOP1 (0.36) | — | |
| SCHEMBL20551511 | 0.71 | CYP2C9 (0.55) | — | |
| SCHEMBL8412940 | 0.71 | CYP2C9 (0.55) | — | |
| SCHEMBL9449589 | 0.71 | CYP2C9 (0.55) | — | |
| SCHEMBL4594305 | 0.71 | — | — | |
| SCHEMBL4594308 | 0.71 | — | — | |
| SCHEMBL249854 | 0.71 | — | — | |
| SCHEMBL249855 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112851588-B | Micro-reaction system and method for continuously preparing 2-methyl-4-amino-5-cyanopyrimidine by using same | 复旦大学 | 2023-04-21 | — | — | CN | claimed |
| US-11554355-B2 | Micro reaction system and method for preparing 2-methyl-4-amino-5-cyanopyrimidine using same | FUDAN UNIVERSITY (CN) | 2023-01-17 | — | — | US | claimed |
| CN-112028791-B | Method for continuously preparing (dimethylamine methylene) malononitrile by using micro-reaction system | 复旦大学 | 2022-11-15 | — | — | CN | claimed |
| US-20210394149-A1 | MICRO REACTION SYSTEM AND METHOD FOR PREPARING 2-METHYL-4-AMINO-5-CYANOPYRIMIDINE USING SAME | FUDAN UNIVERSITY (CN) | 2021-12-23 | — | — | US | claimed |
| CN-113121449-A | Full continuous flow preparation method of 2-methyl-4-amino-5-aminomethyl pyrimidine | 复旦大学 | 2021-07-16 | — | — | CN | claimed |
| CN-112851588-A | Micro-reaction system and method for continuously preparing 2-methyl-4-amino-5-cyanopyrimidine by using same | 复旦大学 | 2021-05-28 | — | — | CN | claimed |
| CN-112028791-A | Method for continuously preparing (dimethylamine methylene) malononitrile by using micro-reaction system | 复旦大学 | 2020-12-04 | — | — | CN | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| US-11708321-B2 | Method for preparing (dimethylaminomethylene) malononitrile using a micro reaction system | FUDAN UNIVERSITY (CN) | 2023-07-25 | — | — | US | disclosed |
| US-11708321-B2 | Method for preparing (dimethylaminomethylene) malononitrile using a micro reaction system | FUDAN UNIVERSITY (CN) | 2023-07-25 | — | — | US | disclosed |
| US-11708321-B2 | Method for preparing (dimethylaminomethylene) malononitrile using a micro reaction system | FUDAN UNIVERSITY (CN) | 2023-07-25 | — | — | US | disclosed |
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |
| US-4180663-A | FORMYLATION OF AROMATIC AMINE, CONDENSATION WITH MALONONITRILE GENERATED IN SITU FROM CYANOACETAMIDE | EASTMAN KODAK COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-3966791-A | Preparation of dialkyl amino acrylonitrile | HOFFMANN-LA ROCHE INC. (US) | 1976-06-29 | — | — | US | disclosed |
| US-3965141-A | Process for producing dialkyl aminoacrylonitrile | HOFFMANN-LA ROCHE INC. (US) | 1976-06-22 | — | — | US | disclosed |