⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249854 | 1.00 | — | — | |
| SCHEMBL26999620 | 0.72 | — | — | |
| SCHEMBL148424 | 0.71 | — | — | |
| SCHEMBL21184103 | 0.69 | — | — | |
| SCHEMBL264678 | 0.69 | — | — | |
| SCHEMBL4594308 | 0.67 | — | — | |
| SCHEMBL10413780 | 0.67 | — | — | |
| SCHEMBL4594305 | 0.67 | — | — | |
| SCHEMBL21028702 | 0.65 | — | — | |
| SCHEMBL24056630 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107793364-A | A kind of method for synthesizing 5 Flucytosines | 新乡拓新药业股份有限公司 | 2018-03-13 | — | — | CN | claimed |
| US-20250243177-A1 | sGC STIMULATORS | CYCLERION THERAPEUTICS, INC. | 2025-07-31 | — | — | US | disclosed |
| CN-107021951-B | sGC stimulators | 赛克里翁治疗有限公司 | 2020-10-20 | — | — | CN | disclosed |
| CN-110105290-B | Preparation method of 5-fluorocytosine | 浙江伟锋药业有限公司 | 2020-06-23 | — | — | CN | disclosed |
| US-20190345130-A1 | SGC STIMULATORS | CYCLERION THERAPEUTICS, INC. | 2019-11-14 | — | — | US | disclosed |
| CN-110105290-A | A kind of preparation method of 5-flurocytosine | 浙江伟锋药业有限公司 | 2019-08-09 | — | — | CN | disclosed |
| US-10189809-B2 | SGC stimulators | IRONWOOD PHARMACEUTICALS, INC. (US) | 2019-01-29 | — | — | US | disclosed |
| CN-107793364-A | A kind of method for synthesizing 5 Flucytosines | 新乡拓新药业股份有限公司 | 2018-03-13 | — | — | CN | disclosed |
| US-20170305878-A1 | sGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2017-10-26 | — | — | US | disclosed |
| EP-3173407-A1 | SGC STIMULATORS | Ironwood Pharmaceuticals, Inc. (US) | 2017-05-31 | — | — | EP | disclosed |
| EP-2588465-B1 | SGC STIMULATORS | IRONWOOD PHARMACEUTICALS INC (US) | 2017-01-25 | — | — | EP | disclosed |
| CN-103313976-B | sGC stimulators | 铁木医药有限公司 | 2016-11-23 | — | — | CN | disclosed |
| US-20140323448-A1 | sGC STIMULATORS | Ironwood Pharmaceuticals Inc. (US) | 2014-10-30 | — | — | US | disclosed |
| US-8748442-B2 | sGC stimulators | IRONWOOD PHARMACEUTICALS, INC. (US) | 2014-06-10 | — | — | US | disclosed |
| EP-2588465-A1 | SGC STIMULATORS | Ironwood Pharmaceuticals, Inc. (US) | 2013-05-08 | — | — | EP | disclosed |
| US-20120184516-A1 | sGC Stimulators | CYCLERION THERAPEUTICS, INC. | 2012-07-19 | — | — | US | disclosed |
| WO-2012003405-A1 | SGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2012-01-05 | — | — | WO | disclosed |