SCHEMBL14844698

SCHEMBL14844698

O=C(O)S(=O)(=O)c1ccc2ccccc2c1

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.57
ALDH1A1 P00352 4/20 0.54
KAT6A Q92794 3/20 0.53
L3MBTL1 Q9Y468 1/20 0.52
F2 P00734 2/20 0.51
PRSS1 P07477 2/20 0.51
PRSS2 P07478 2/20 0.51
PRSS3 P35030 2/20 0.51
AKR1C3 P42330 2/20 0.49
AKR1C1 Q04828 2/20 0.49
SLC1A3 P43003 1/20 0.49
SLC1A2 P43004 1/20 0.49
SLC1A1 P43005 1/20 0.49
CA2 P00918 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
GAA P10253 2/20 0.47
HTT P42858 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL7292653 0.80 SNCA (0.64) LMNAALDH1A1KAT6AL3MBTL1F2
SCHEMBL7137356 0.79 CES2 (0.55) LMNAALDH1A1KAT6AF2PRSS1
SCHEMBL14029051 0.79 GAA (0.63) LMNAALDH1A1KAT6AGAAHTT
Oxalic Acid SCHEMBL8992177 0.78 SNCA (0.62) LMNAALDH1A1KAT6AL3MBTL1F2
SCHEMBL304050 0.77 SNCA (0.65) LMNAALDH1A1L3MBTL1F2PRSS1
SCHEMBL1556 0.77 SNCA (0.65) LMNAALDH1A1L3MBTL1F2PRSS1
SCHEMBL29357423 0.77 SNCA (0.65) LMNAALDH1A1L3MBTL1F2PRSS1
SCHEMBL29857297 0.77 SNCA (0.65) LMNAALDH1A1L3MBTL1F2PRSS1
Naphthalene SCHEMBL28216326 0.77 SNCA (0.65) LMNAALDH1A1L3MBTL1F2PRSS1
SCHEMBL28275730 0.77 SNCA (0.65) LMNAALDH1A1L3MBTL1F2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140234883-A1 USE OF PHOTOCLEAVABLE COMPOUNDS FEMTONICS KFT (HU) 2014-08-21 US claimed
EP-2763965-A2 USE OF PHOTOCLEAVABLE COMPOUNDS Femtonics Kft. (HU) 2014-08-13 EP claimed
WO-2013050798-A2 USE OF PHOTOCLEAVABLE COMPOUNDS FEMTONICS KFT. (HU) 2013-04-11 WO claimed
WO-2013050795-A1 USE OF PHOTOACTIVE COMPOUNDS FEMTONICS KFT. (HU) 2013-04-11 WO claimed
WO-2013050795-A1 USE OF PHOTOACTIVE COMPOUNDS FEMTONICS KFT. (HU) 2013-04-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140234883-A1 USE OF PHOTOCLEAVABLE COMPOUNDS ERCC1, ERCC4, ERCC5 LMNA 613/4885ALDH1A1 2733/4885KAT6A 4015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.