Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.48 |
| ▸ | CTSS | P25774 | 7/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28000286 | 0.82 | CTSK (0.52) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL21419058 | 0.82 | CTSK (0.52) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL8141271 | 0.81 | CTSS (0.49) | CTSKCTSSKMT2ACTSLCTSB | |
| SCHEMBL23036809 | 0.81 | CTSS (0.49) | CTSKCTSSKMT2ACTSLCTSB | |
| SCHEMBL24340590 | 0.81 | CTSK (0.48) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL23273778 | 0.81 | CTSS (0.49) | CTSKCTSSKMT2ACTSLCTSB | |
| SCHEMBL25166215 | 0.80 | CA1 (0.46) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL31059710 | 0.80 | CA1 (0.46) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL31059527 | 0.80 | CA1 (0.46) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL17627333 | 0.79 | CTSK (0.47) | CTSKCTSSCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8415486-B2 | IAP inhibitors | TETRALOGIC PHARMACEUTICALS CORP. (US) | 2013-04-09 | — | — | US | disclosed |