Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | POLRMT | O00411 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14845682 | 0.93 | TMPRSS2 (0.33) | TMPRSS2 | |
| SCHEMBL14845672 | 0.93 | TMPRSS2 (0.34) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL14845675 | 0.91 | TMPRSS2 (0.31) | TMPRSS2CSNK2A2CSNK2A1 | |
| SCHEMBL10142407 | 0.89 | TMPRSS2 (0.34) | TMPRSS2POLRMT | |
| SCHEMBL10120830 | 0.87 | TMPRSS2 (0.46) | TMPRSS2CSNK2A2CSNK2A1RIPK1POLRMT | |
| SCHEMBL18310024 | 0.85 | TMPRSS2 (0.46) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL10154374 | 0.85 | TMPRSS2 (0.33) | TMPRSS2CSNK2A2CSNK2A1RIPK1POLRMT | |
| SCHEMBL14845677 | 0.85 | TMPRSS2 (0.30) | TMPRSS2 | |
| SCHEMBL18666928 | 0.84 | POLRMT (0.34) | TMPRSS2CSNK2A2CSNK2A1RIPK1POLRMT | |
| SCHEMBL20762571 | 0.84 | POLRMT (0.34) | TMPRSS2CSNK2A2CSNK2A1RIPK1POLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8415308-B2 | 1′-substituted-carba-nucleoside prodrugs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2013-04-09 | — | — | US | disclosed |