Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18061173 | 0.89 | MET (0.48) | METCYP3A4 | |
| SCHEMBL9910347 | 0.71 | MET (0.83) | METCYP3A4 | |
| SCHEMBL18061169 | 0.69 | MET (0.61) | MET | |
| SCHEMBL18885789 | 0.68 | MET (0.45) | METCYP3A4 | |
| SCHEMBL4900121 | 0.67 | MET (0.54) | METCYP3A4 | |
| SCHEMBL9910302 | 0.67 | MET (0.84) | METCYP3A4 | |
| SCHEMBL29878429 | 0.66 | MET (0.54) | METCYP3A4 | |
| SCHEMBL2700581 | 0.66 | MET (0.54) | METCYP3A4 | |
| SCHEMBL3839146 | 0.65 | TLR8 (0.60) | METCYP3A4 | |
| SCHEMBL8145365 | 0.64 | HTR1A (0.61) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2578583-A1 | Fused heterocyclic derivatives and methods of use | Amgen Inc. (US) | 2013-04-10 | — | — | EP | disclosed |