Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 4/20 | 0.38 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14848838 | 0.99 | STAT3 (0.44) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL30733335 | 0.93 | STAT3 (0.47) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL15298526 | 0.86 | STAT3 (0.41) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL15282931 | 0.83 | STAT3 (0.44) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL9425127 | 0.81 | PDE5A (0.41) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL14841979 | 0.80 | STAT3 (0.47) | STAT3STAT1MCHR1TLR8MAPT | |
| SCHEMBL5100067 | 0.80 | STAT3 (0.47) | STAT3STAT1MCHR1 | |
| SCHEMBL29140523 | 0.78 | PDE5A (0.37) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL21523873 | 0.78 | STAT3 (0.53) | STAT3STAT1MAPTLMNAHTT | |
| SCHEMBL29140531 | 0.78 | PDE5A (0.43) | PDE5APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090469-A1 | GREEN ZINC PORPHYRIN SENSITIZERS AND THEIR APPLICATIONS | NATIONAL CHUNG HSING UNIVERSITY (TW) | 2013-04-11 | — | — | US | disclosed |