Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 8/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 7/20 | 0.33 |
| ▸ | HTR1A | P08908 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15298526 | 0.94 | STAT3 (0.41) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL30733335 | 0.90 | STAT3 (0.47) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL29395084 | 0.88 | STAT3 (0.50) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL28879055 | 0.87 | STAT3 (0.49) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL21523873 | 0.86 | STAT3 (0.53) | STAT3STAT1MAPTPLA2G2AKDM4E | |
| SCHEMBL14848838 | 0.84 | STAT3 (0.44) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL14848833 | 0.83 | STAT3 (0.45) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL14848717 | 0.83 | STAT3 (0.47) | STAT3STAT1TSHRHTR1BGABRA1 | |
| Hydrochloric Acid SCHEMBL27856204 | 0.83 | STAT3 (0.50) | STAT3STAT1MAPTMAPK1TDP1 | |
| SCHEMBL585094 | 0.81 | STAT3 (0.48) | STAT3STAT1MAPTPLA2G2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150273457-A1 | HIGHLY ACTIVE MULTIDENTATE CATALYSTS FOR EFFICIENT ALKYNE METATHESIS | NATIONAL SCIENCE FOUNDATION | 2015-10-01 | — | — | US | disclosed |
| US-8993804-B2 | Highly active multidentate catalysts for efficient alkyne metathesis | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2015-03-31 | — | — | US | disclosed |
| US-20130261295-A1 | Highly Active Multidentate Catalysts for Efficient Alkyne Metathesis | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2013-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150273457-A1 | HIGHLY ACTIVE MULTIDENTATE CATALYSTS FOR EFFICIENT ALKYNE METATHESIS | PCNA, TRIM58, CAD | STAT3 3890/4885STAT1 4442/4885PDE5A 4852/4885 |
| US-20130261295-A1 | Highly Active Multidentate Catalysts for Efficient Alkyne Metathesis | PCNA, TRIM58, CAD | STAT3 3890/4885STAT1 4442/4885PDE5A 4852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.