Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 4/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14848833 | 0.99 | STAT3 (0.45) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL30733335 | 0.94 | STAT3 (0.47) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL15298526 | 0.87 | STAT3 (0.41) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL15282931 | 0.84 | STAT3 (0.44) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL9425127 | 0.82 | PDE5A (0.41) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL29140523 | 0.79 | PDE5A (0.37) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL14841979 | 0.79 | STAT3 (0.47) | STAT3STAT1MCHR1TLR8MAPT | |
| SCHEMBL5100067 | 0.79 | STAT3 (0.47) | STAT3STAT1MCHR1 | |
| SCHEMBL21523873 | 0.79 | STAT3 (0.53) | STAT3STAT1MAPTLMNACYP3A4 | |
| SCHEMBL29140531 | 0.79 | PDE5A (0.43) | PDE5APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090469-A1 | GREEN ZINC PORPHYRIN SENSITIZERS AND THEIR APPLICATIONS | NATIONAL CHUNG HSING UNIVERSITY (TW) | 2013-04-11 | — | — | US | disclosed |