Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.65 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.65 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19879702 | 0.87 | ADRA2A (0.56) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL22681610 | 0.85 | ADRA2A (0.55) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL15981868 | 0.82 | MAPT (0.53) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL15981857 | 0.82 | MAPT (0.53) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL21600799 | 0.80 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL16340275 | 0.79 | HPGD (0.54) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL16340696 | 0.79 | EGFR (0.51) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL25541795 | 0.79 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL16222297 | 0.77 | LMNA (0.59) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL12909341 | 0.76 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090469-A1 | GREEN ZINC PORPHYRIN SENSITIZERS AND THEIR APPLICATIONS | NATIONAL CHUNG HSING UNIVERSITY (TW) | 2013-04-11 | — | — | US | disclosed |