Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6355390 | 0.81 | MEN1 (0.43) | MEN1POLBKMT2AALDH1A1TDP1 | |
| SCHEMBL2551561 | 0.81 | MAOA (0.48) | MAOAMAOBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL20048186 | 0.79 | SKP2 (0.50) | POLBKMT2AALDH1A1RAB9ACYP1A2 | |
| SCHEMBL18353303 | 0.79 | SKP2 (0.50) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL27619133 | 0.79 | SKP2 (0.41) | MEN1POLBKMT2AALDH1A1TDP1 | |
| SCHEMBL31753689 | 0.78 | ALDH1A1 (0.47) | MEN1POLBKMT2AALDH1A1TDP1 | |
| SCHEMBL5524133 | 0.78 | TAAR1 (0.50) | ALDH1A1TDP1CYP1A2CYP2D6ALOX15 | |
| SCHEMBL11279849 | 0.78 | ALDH1A1 (0.47) | MEN1POLBKMT2AALDH1A1TDP1 | |
| SCHEMBL3192065 | 0.76 | SKP2 (0.47) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL7638694 | 0.76 | TAAR1 (0.48) | MEN1KMT2AALDH1A1TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346770-B2 | Compounds having activating effect on subtypes of peroxisome proliferator-activated receptors and its preparation method and uses | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2016-05-24 | — | — | US | disclosed |
| US-20130089613-A1 | Compounds Having Activating Effect on Subtypes of Peroxisome Proliferator-Activated Receptors and its Preparation Method and Uses | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2013-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130089613-A1 | Compounds Having Activating Effect on Subtypes of Peroxisome Proliferator-Activated Receptors and its Preparation Method and Uses | PPARA, PPARG, PPARD | MEN1 4866/4885POLB 960/4885KMT2A 3291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.