Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 19/20 | 0.82 |
| ▸ | MMP2 | P08253 | 12/20 | 0.82 |
| ▸ | MMP3 | P08254 | 11/20 | 0.82 |
| ▸ | MMP13 | P45452 | 18/20 | 0.76 |
| ▸ | MMP9 | P14780 | 10/20 | 0.76 |
| ▸ | MMP7 | P09237 | 8/20 | 0.76 |
| ▸ | MMP8 | P22894 | 6/20 | 0.76 |
| ▸ | MMP14 | P50281 | 2/20 | 0.72 |
| ▸ | ADAM17 | P78536 | 11/20 | 0.69 |
| ▸ | ADAM10 | O14672 | 2/20 | 0.64 |
| ▸ | ADAM9 | Q13443 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14843285 | 1.00 | MMP1 (0.82) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL6768915 | 0.97 | MMP1 (0.88) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL6338635 | 0.94 | MMP1 (0.83) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL14843316 | 0.89 | MMP1 (0.78) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL14850444 | 0.89 | MMP1 (0.78) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL6775107 | 0.89 | MMP1 (0.76) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL14843152 | 0.88 | MMP1 (0.82) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL14850433 | 0.88 | MMP1 (0.82) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL6775653 | 0.88 | MMP1 (0.71) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL14850445 | 0.88 | MMP1 (0.72) | MMP1MMP2MMP3MMP13MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9193699-B2 | Apoptosis inducing compounds | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM (FR) | 2015-11-24 | — | — | US | disclosed |
| US-9193699-B2 | Apoptosis inducing compounds | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM (FR) | 2015-11-24 | — | — | US | disclosed |
| US-20140296227-A1 | APOPTOSIS INDUCING COMPOUNDS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2014-10-02 | — | — | US | disclosed |
| US-20140296227-A1 | APOPTOSIS INDUCING COMPOUNDS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2014-10-02 | — | — | US | disclosed |
| WO-2013050476-A1 | NEW APOPTOSIS INDUCING COMPOUNDS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2013-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296227-A1 | APOPTOSIS INDUCING COMPOUNDS | BAX, BCL2, CASP3 | MMP1 3754/4885MMP2 3209/4885MMP3 3144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.