Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32664934 | 0.86 | ALDH1A1 (0.56) | HPGDKDM4EHSD17B10TSHRHTT | |
| SCHEMBL16456325 | 0.85 | KDM4E (0.55) | HPGDKDM4EHSD17B10TSHRHTT | |
| SCHEMBL15365749 | 0.83 | HSD17B10 (0.58) | HPGDKDM4EHSD17B10TSHRHTT | |
| SCHEMBL4784567 | 0.83 | BRD4 (0.65) | HPGDKDM4EHSD17B10HTTALDH1A1 | |
| SCHEMBL16455949 | 0.80 | ALDH1A1 (0.50) | HPGDKDM4EHSD17B10TSHRHTT | |
| SCHEMBL15364821 | 0.80 | ALDH1A1 (0.50) | HPGDKDM4EHSD17B10TSHRHTT | |
| SCHEMBL16456310 | 0.80 | KDM4E (0.49) | HPGDKDM4EHSD17B10TSHRHTT | |
| SCHEMBL14765168 | 0.80 | KDM4E (0.64) | KDM4EALDH1A1SMN1; SMN2PIM1 | |
| SCHEMBL15364726 | 0.80 | ALDH1A1 (0.66) | HPGDKDM4EHSD17B10TSHRHTT | |
| SCHEMBL32665254 | 0.79 | ALDH1A1 (0.51) | HPGDKDM4EHSD17B10TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013051672-A1 | MEDICINAL AGENT COMPRISING THIAZOLIDINE DERIVATIVE OR SALT THEREOF AS ACTIVE INGREDIENT | 株式会社ヤクルト本社 (JP) | 2013-04-11 | — | — | WO | disclosed |