Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 6/20 | 0.69 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.69 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.69 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.69 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.69 |
| ▸ | TOP2A | P11388 | 2/20 | 0.57 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8229714 | 0.89 | PRMT1 (0.71) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL8238119 | 0.87 | PRMT1 (0.69) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL362453 | 0.86 | PRMT1 (0.68) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| Hydrochloric Acid SCHEMBL3383477 | 0.85 | PRMT1 (0.66) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14535010 | 0.85 | PRMT1 (0.70) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14854501 | 0.83 | PRMT1 (0.74) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL31621368 | 0.83 | PRMT1 (0.66) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL13204583 | 0.82 | PRMT1 (1.00) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL15727407 | 0.81 | PRMT1 (0.62) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14816979 | 0.81 | PRMT1 (0.65) | PRMT1PRMT3EHMT2PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013052263-A2 | ANTIFUNGAL COMPOUNDS | MICROBIOTIX, INC. (US) | 2013-04-11 | — | — | WO | disclosed |