Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 5/20 | 0.66 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.66 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.66 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.66 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.66 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL362453 | 0.98 | PRMT1 (0.68) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL8238119 | 0.97 | PRMT1 (0.69) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL8229714 | 0.92 | PRMT1 (0.71) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14535010 | 0.91 | PRMT1 (0.70) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL13204586 | 0.91 | PRMT1 (0.62) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL15727407 | 0.90 | PRMT1 (0.62) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL31621368 | 0.89 | PRMT1 (0.66) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14854537 | 0.88 | PRMT1 (0.59) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL15727389 | 0.85 | PRMT1 (0.56) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14854499 | 0.85 | PRMT1 (0.61) | PRMT1PRMT3EHMT2PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239283-B1 | Method for the identification and counting of biological cells | ABX SA (FR) | 2010-12-01 | — | — | EP | claimed |
| US-20020182623-A1 | Reagent and process for the identification and counting of biological cells | ABX (FR) | 2002-12-05 | — | — | US | claimed |
| EP-3382035-B1 | CELLULAR ANALYSIS OF BODY FLUIDS | ABBOTT LAB (US) | 2021-08-11 | — | — | EP | disclosed |
| US-20210130866-A1 | Cellular Analysis of Body Fluids | ABBOTT LABORATORIES | 2021-05-06 | — | — | US | disclosed |
| US-10774359-B2 | Cellular analysis of body fluids | ABBOTT LABORATORIES (US) | 2020-09-15 | — | — | US | disclosed |
| US-20180334699-A1 | Cellular Analysis of Body Fluids | ABBOTT LABORATORIES | 2018-11-22 | — | — | US | disclosed |
| EP-3382035-A1 | CELLULAR ANALYSIS OF BODY FLUIDS | Abbott Laboratories (US) | 2018-10-03 | — | — | EP | disclosed |
| US-9970045-B2 | Cellular analysis of body fluids | ABBOTT LABORATORIES (US) | 2018-05-15 | — | — | US | disclosed |
| EP-2798087-B1 | CELLULAR ANALYSIS OF BODY FLUIDS | ABBOTT LAB (US) | 2018-03-07 | — | — | EP | disclosed |
| EP-2798087-A1 | CELLULAR ANALYSIS OF BODY FLUIDS | ABBOTT LABORATORIES (US) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013101603-A1 | CELLULAR ANALYSIS OF BODY FLUIDS | ABBOTT LABORATORIES (US) | 2013-07-04 | — | — | WO | disclosed |
| US-20130164740-A1 | Cellular Analysis of Body Fluids | ABBOTT LABORATORIES (US) | 2013-06-27 | — | — | US | disclosed |
| US-20110318733-A1 | TEST SYSTEM AND METHOD FOR THE DETECTION OF ANALYTES | DADE BEHRING MARBURG GMBH | 2011-12-29 | — | — | US | disclosed |
| US-20080227086-A1 | Test System and Method for the Detection of Analytes | SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) | 2008-09-18 | — | — | US | disclosed |
| US-20070111276-A1 | Reagent and process for the identification and counting of biological cells | ABX (FR) | 2007-05-17 | — | — | US | disclosed |
| US-20020182623-A1 | Reagent and process for the identification and counting of biological cells | ABX (FR) | 2002-12-05 | — | — | US | disclosed |