Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 5/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752284 | 0.86 | CHRM3 (0.38) | CHRM2CHRM1CYP3A4ALDH1A1CHRM3 | |
| SCHEMBL2167352 | 0.86 | CHRM3 (0.38) | CHRM2CHRM1CYP3A4ALDH1A1CHRM3 | |
| SCHEMBL722593 | 0.86 | CHRM3 (0.38) | CHRM2CHRM1CYP3A4ALDH1A1CHRM3 | |
| SCHEMBL11295974 | 0.81 | ALDH1A1 (0.38) | CHRM2CHRM1CYP3A4ALDH1A1CHRM3 | |
| SCHEMBL4659036 | 0.78 | CHRM2 (0.51) | CHRM2CHRM1CYP3A4ALDH1A1MAPT | |
| SCHEMBL4660409 | 0.78 | CHRM2 (0.51) | CHRM2CHRM1CYP3A4ALDH1A1MAPT | |
| SCHEMBL4189998 | 0.78 | MAPT (0.38) | CHRM2CHRM1ALDH1A1CHRM3CHRM5 | |
| SCHEMBL11297464 | 0.77 | CHRM2 (0.48) | CHRM2CHRM1 | |
| SCHEMBL7758289 | 0.77 | MAPT (0.41) | ALDH1A1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL4660292 | 0.77 | CHRM2 (0.48) | CHRM2CHRM1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2580203-A1 | PROCESS FOR THE PREPARATION OF 2 -HYDROXY- 4 -PHENYL -3, 4 -DIHYDRO-2H-CHROMEN- 6 -YL -METHANOL AND (R) - FESO - DEACYL | Chemi SPA (IT) | 2013-04-17 | — | — | EP | disclosed |
| WO-2011154854-A1 | PROCESS FOR THE PREPARATION OF 2 -HYDROXY- 4 -PHENYL -3, 4 -DIHYDRO-2H-CHROMEN- 6 -YL -METHANOL AND (R) - FESO - DEACYL | CHEMI SPA (IT) | 2011-12-15 | — | — | WO | disclosed |