Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11295974 | 0.89 | ALDH1A1 (0.38) | MAPTKMT2ATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15559016 | 0.85 | THRA (0.34) | MAPTKMT2ATDP1SMN1; SMN2LMNA | |
| SCHEMBL15541447 | 0.83 | CHRM3 (0.35) | MAPTKMT2ATDP1SMN1; SMN2HPGD | |
| SCHEMBL7758295 | 0.83 | BCHE (0.38) | MAPTKMT2ATDP1SMN1; SMN2LMNA | |
| SCHEMBL7756317 | 0.81 | BCHE (0.36) | MAPTNPC1KMT2ATDP1ALDH1A1 | |
| SCHEMBL7752344 | 0.81 | BCHE (0.36) | MAPTKMT2ALMNA | |
| SCHEMBL7752284 | 0.81 | CHRM3 (0.38) | MAPTKMT2ATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2167352 | 0.81 | CHRM3 (0.38) | MAPTKMT2ATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL722593 | 0.81 | CHRM3 (0.38) | MAPTKMT2ATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7755082 | 0.80 | BCHE (0.35) | MAPTKMT2ATDP1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077912-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058478-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 1999-11-18 | — | — | WO | disclosed |