Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 7/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14856668 | 0.93 | CNR2 (0.36) | CNR2L3MBTL1TRPV1P2RX7FAAH | |
| SCHEMBL14856721 | 0.90 | CNR2 (0.38) | CNR2L3MBTL1TRPV1P2RX7FAAH | |
| SCHEMBL14856623 | 0.89 | CNR2 (0.37) | CNR2TRPV1P2RX7FAAHCYP1A2 | |
| SCHEMBL14856808 | 0.89 | CNR2 (0.38) | CNR2TRPV1P2RX7FAAH | |
| SCHEMBL2807122 | 0.89 | AR (0.37) | CNR2L3MBTL1ARCTSLP2RX7 | |
| SCHEMBL14856247 | 0.88 | CNR2 (0.36) | CNR2TRPV1P2RX7FAAHCYP1A2 | |
| SCHEMBL14856769 | 0.88 | CNR2 (0.36) | CNR2TRPV1P2RX7FAAHRAB9A | |
| SCHEMBL14856764 | 0.88 | FLT3 (0.36) | CNR2TRPV1P2RX7FAAH | |
| SCHEMBL250768 | 0.87 | CNR2 (0.36) | CNR2TRPV1P2RX7FAAH | |
| SCHEMBL14856723 | 0.87 | CNR2 (0.36) | CNR2L3MBTL1TRPV1P2RX7FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |