Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14856247 | 0.93 | CNR2 (0.36) | CNR2ALDH1A1HTR2AHTR2CLMNA | |
| SCHEMBL14856774 | 0.92 | FAAH (0.34) | TRPV1FAAHMAPK10P2RX7BDKRB1 | |
| SCHEMBL14856668 | 0.92 | CNR2 (0.36) | CNR2LMNAKDM4ETRPV1FAAH | |
| SCHEMBL14856670 | 0.91 | FAAH (0.35) | CNR2TRPV1FAAHP2RX7BDKRB1 | |
| SCHEMBL14856623 | 0.91 | CNR2 (0.37) | CNR2HTR2AHTR2CLMNATRPV1 | |
| SCHEMBL14856721 | 0.91 | CNR2 (0.38) | CNR2TRPV1FAAHNTRK1P2RX7 | |
| SCHEMBL14856769 | 0.90 | CNR2 (0.36) | CNR2ALDH1A1LMNAKDM4ETRPV1 | |
| SCHEMBL2806105 | 0.89 | CNR2 (0.39) | CNR2ALDH1A1ATMHTR2AHTR2C | |
| SCHEMBL14856464 | 0.89 | CNR2 (0.35) | CNR2TRPV1FAAHP2RX7 | |
| SCHEMBL14856723 | 0.89 | CNR2 (0.36) | CNR2LMNATRPV1FAAHNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |