Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2811620 | 1.00 | RAB9A (0.39) | RAB9ACYP1A2CYP2D6CYP2C19GAA | |
| SCHEMBL2811623 | 1.00 | RAB9A (0.39) | RAB9ACYP1A2CYP2D6CYP2C19GAA | |
| SCHEMBL2808251 | 0.88 | KIT (0.38) | FLT3KITKDM4EDHODHKDR | |
| SCHEMBL2808253 | 0.88 | KIT (0.38) | FLT3KITKDM4EDHODHKDR | |
| SCHEMBL185082 | 0.88 | KIT (0.38) | FLT3KITKDM4EDHODHKDR | |
| SCHEMBL184859 | 0.86 | OPRM1 (0.37) | CYP2D6FLT3KITKDM4EDHODH | |
| SCHEMBL2811511 | 0.86 | OPRM1 (0.37) | CYP2D6FLT3KITKDM4EDHODH | |
| SCHEMBL186306 | 0.86 | RAB9A (0.46) | RAB9ACYP1A2CYP2D6CYP2C19GAA | |
| SCHEMBL2808003 | 0.83 | KDM4E (0.41) | GAATP53MAPTSMN1; SMN2FLT3 | |
| SCHEMBL2808006 | 0.83 | KDM4E (0.41) | GAATP53MAPTSMN1; SMN2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |