Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 8/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | TEK | Q02763 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2809567 | 0.88 | POLB (0.38) | CDK1CNR2L3MBTL1POLB | |
| SCHEMBL14857251 | 0.86 | CNR2 (0.36) | CNR2TRPV1P2RX7L3MBTL1FAAH | |
| SCHEMBL14856723 | 0.86 | CNR2 (0.36) | CNR2TRPV1NTRK1P2RX7L3MBTL1 | |
| SCHEMBL14856668 | 0.85 | CNR2 (0.36) | CNR2TRPV1P2RX7L3MBTL1FAAH | |
| SCHEMBL14856749 | 0.85 | CNR2 (0.35) | CNR2TRPV1P2RX7FAAH | |
| SCHEMBL14856721 | 0.85 | CNR2 (0.38) | CNR2TRPV1NTRK1P2RX7L3MBTL1 | |
| SCHEMBL14856628 | 0.84 | FAAH (0.33) | CDK1CNR2TRPV1P2RX7FAAH | |
| SCHEMBL14856551 | 0.84 | CNR2 (0.34) | CNR2TRPV1P2RX7L3MBTL1FAAH | |
| SCHEMBL14856623 | 0.83 | CNR2 (0.37) | CNR2TRPV1P2RX7PTK2FAAH | |
| SCHEMBL14856808 | 0.83 | CNR2 (0.38) | CNR2TRPV1NTRK1P2RX7FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |