SCHEMBL1485928

SCHEMBL1485928

O=S(=O)(O)c1ccc2c(ccc3nn[nH]c32)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 4/20 0.45
CYP2C9 P11712 3/20 0.45
HSD17B10 Q99714 3/20 0.45
CYP2C19 P33261 2/20 0.45
ALDH1A1 P00352 2/20 0.45
NT5E P21589 2/20 0.40
HDAC6 Q9UBN7 1/20 0.39
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
THRB P10828 2/20 0.38
APEX1 P27695 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
CYP1A2 P05177 2/20 0.38
NSD2 O96028 3/20 0.38
PTPN11 Q06124 3/20 0.37
SNCA P37840 2/20 0.37
DUSP3 P51452 2/20 0.37
PTPN5 P54829 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1485877 0.81 CASP6 (0.35) CASP6CYP2C9HSD17B10CYP2C19ALDH1A1
SCHEMBL11407010 0.81 ALDH1A1 (0.38) CASP6CYP2C9HSD17B10CYP2C19ALDH1A1
SCHEMBL1485803 0.80 SUMO2 (0.41) CASP6CYP2C9HSD17B10CYP2C19ALDH1A1
SCHEMBL12849326 0.74 HDAC6 (0.48) CASP6CYP2C9HSD17B10CYP2C19ALDH1A1
SCHEMBL16454178 0.72 CASP6 (0.50) CASP6CYP2C9HSD17B10CYP2C19ALDH1A1
SCHEMBL1156233 0.71 HDAC6 (0.41) CASP6CYP2C9HSD17B10CYP2C19ALDH1A1
SCHEMBL10495179 0.71 CYP3A4 (0.41) HSD17B10ALDH1A1MEN1KMT2ATDP1
SCHEMBL9453804 0.70 HDAC6 (0.40) CASP6CYP2C9HSD17B10CYP2C19ALDH1A1
SCHEMBL8423877 0.70 HDAC6 (0.40) CASP6CYP2C9HSD17B10CYP2C19ALDH1A1
Ammonia Solution, Strong SCHEMBL6052135 0.70 HDAC6 (0.40) CASP6CYP2C9HSD17B10CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2674461-B1 AZO COMPOUND, DYE-BASED POLARIZING FILM, AND POLARIZING PLATE NIPPON KAYAKU KK (JP) 2019-03-27 EP disclosed
US-20190048194-A1 Azo Compound Or Salt Thereof, And Polarizing Film Containing Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2019-02-14 US disclosed
EP-3421546-A1 AZO COMPOUND OR SALT THEREOF, AND POLARIZING FILM CONTAINING SAME Nippon Kayaku Kabushiki Kaisha (JP) 2019-01-02 EP disclosed
US-10150871-B2 Azo compound, dye-based polarizing film containing same, and polarizing plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2018-12-11 US disclosed
US-20170210902-A1 Azo Compound, Dye-Based Polarizing Film Containing Same, And Polarizing Plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2017-07-27 US disclosed
EP-3127965-A1 AZO COMPOUND, DYE-BASED POLARIZING FILM CONTAINING SAME, AND POLARIZING PLATE Nippon Kayaku Kabushiki Kaisha (JP) 2017-02-08 EP disclosed
US-9354371-B2 Azo compounds, and dye-based polarizing films and polarizing plates comprising the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-05-31 US disclosed
US-9341746-B2 Azo compound, dye-based polarizing film and polarizing plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-05-17 US disclosed
US-20160109619-A1 Azo Compound, Dye-Based Polarizing Film And Polarizing Plate POLATECHNO CO LTD (JP) 2016-04-21 US disclosed
US-9244194-B2 Azo compound and salt thereof, and dye-based polarizing film and polarizing plate containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-01-26 US disclosed
US-9244198-B2 Azo compound, dye-based polarizing film and polarizing plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-01-26 US disclosed
US-20150331148-A1 Azo Compound, Dye-Based Polarizing Film And Polarizing Plate NIPPON KAYAKU KK (JP) 2015-11-19 US disclosed
US-20140218797-A1 Polarizing Element And Polarizing Plate POLATECHNO CO., LTD. (JP) 2014-08-07 US disclosed
EP-2752694-A1 POLARIZING ELEMENT AND POLARIZING PLATE Nippon Kayaku Kabushiki Kaisha (JP) 2014-07-09 EP disclosed
EP-2674461-A1 AZO COMPOUND, DYE-BASED POLARIZING FILM, AND POLARIZING PLATE Nippon Kayaku Kabushiki Kaisha (JP) 2013-12-18 EP disclosed
US-20130314786-A1 Azo Compound And Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same POLATECHNO CO., LTD. (JP) 2013-11-28 US disclosed
US-20130302538-A1 Azo Compound, Dye-Based Polarizing Film And Polarizing Plate POLATECHNO CO., LTD. (JP) 2013-11-14 US disclosed
US-8477268-B2 Azo compound and salts thereof, as well as dye-based polarization films and polarizing plates comprising the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-07-02 US disclosed
US-20110164208-A1 Azo Compound And Salts Thereof, As Well As Dye-Based Polarization Films And Polarizing Plates Comprising The Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-07 US disclosed
US-20110075076-A1 Azo Compounds, And Dye-Based Polarizing Films And Polarizing Plates Comprising The Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-03-31 US disclosed