SCHEMBL1485976

SCHEMBL1485976

COC(=O)[C@@](C)(N)Cc1ccc(O)c(O)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 6/20 0.69
KDM4E B2RXH2 5/20 0.69
MAPT P10636 5/20 0.69
HPGD P15428 4/20 0.69
ALDH1A1 P00352 4/20 0.69
TDP1 Q9NUW8 4/20 0.69
ALOX15 P16050 4/20 0.69
BLM P54132 4/20 0.69
POLB P06746 3/20 0.69
CYP1A2 P05177 3/20 0.69
GAA P10253 3/20 0.69
CYP3A4 P08684 2/20 0.69
APEX1 P27695 2/20 0.69
PMP22 Q01453 2/20 0.69
USP2 O75604 2/20 0.69
EGFR P00533 2/20 0.69
FYN P06241 2/20 0.69
PTGS2 P35354 2/20 0.69
RECQL P46063 2/20 0.69
MEN1 O00255 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1485974 1.00 HSD17B10 (0.69) HSD17B10KDM4EMAPTHPGDALDH1A1
SCHEMBL29881847 1.00 HSD17B10 (0.69) HSD17B10KDM4EMAPTHPGDALDH1A1
SCHEMBL30002544 0.87 KDM4E (0.52) HSD17B10KDM4EMAPTHPGDALDH1A1
SCHEMBL24761175 0.86 KDM4E (0.68) HSD17B10KDM4EMAPTHPGDALDH1A1
Methyldopate SCHEMBL297359 0.85 HSD17B10 (0.66) HSD17B10KDM4EMAPTHPGDALDH1A1
Methyldopate SCHEMBL11430187 0.85 HSD17B10 (0.66) HSD17B10KDM4EMAPTHPGDALDH1A1
Methyldopate SCHEMBL29587132 0.85 HSD17B10 (0.66) HSD17B10KDM4EMAPTHPGDALDH1A1
Hydrochloric Acid SCHEMBL28027363 0.84 KDM4E (0.56) HSD17B10KDM4EMAPTHPGDALDH1A1
SCHEMBL11850560 0.84 KDM4E (0.61) HSD17B10KDM4EMAPTHPGDALDH1A1
SCHEMBL24761068 0.84 KDM4E (0.64) HSD17B10KDM4EMAPTHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180193209-A1 A POLYMER PRODUCT AND PREPARATION THEROF SINGAPORE HEALTH SERVICES PTE LTD. (SG) 2018-07-12 US claimed
EP-3319779-A1 A POLYMER PRODUCT AND PREPARATION THEREOF Singapore Health Services Pte Ltd (SG) 2018-05-16 EP claimed
US-20110136704-A1 Methods of Treating a Hydrocarbon-Bearing Formation, a Well Bore, and Particles BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2011-06-09 US claimed
EP-2300558-A2 METHODS OF TREATING A HYDROCARBON-BEARING FORMATION, A WELL BORE, AND PARTICLES Board of Regents, The University of Texas System (US) 2011-03-30 EP claimed
WO-2009148831-A2 METHODS OF TREATING A HYDROCARBON-BEARING FORMATION, A WELL BORE, AND PARTICLES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2009-12-10 WO claimed
EP-4731266-A1 NANOPARTICLE COMPOSITIONS ASSOCIATED WITH PEPTIDES The Regents of the University of Michigan (US) 2026-04-29 EP disclosed
US-20260108618-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2026-04-23 US disclosed
US-12569565-B2 Compositions and methods for the treatment of viral infections CIDARA THERAPEUTICS, INC. (US) 2026-03-10 US disclosed
US-20260000781-A1 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF CIDARA THERAPEUTICS INC (US) 2026-01-01 US disclosed
US-20250325644-A1 ALK POLYPEPTIDES AND METHODS OF USE THEREOF ELICIO THERAPEUTICS INC (US) 2025-10-23 US disclosed
EP-4627079-A2 THERMOSTABLE BINDING SCAFFOLDS Nectagen, Inc. (US) 2025-10-08 EP disclosed
US-12427200-B2 Compositions and methods for the treatment of viral infections CIDARA THERAPEUTICS, INC. (US) 2025-09-30 US disclosed
WO-2007042848-A2 PROCESS FOR THE PREPARATION OF CARBIDOPA EGIS GYÓGYSZERGYÁR (HU) 2007-04-19 WO disclosed
EP-0821551-B1 SCREENING ASSAY FOR THE IDENTIFICATION OF INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR PICOWER INST MED RES (US) 2004-10-06 EP disclosed
US-20030105014-A1 Preparing reaction mixture of macrophage migration inhibitory factor(MIF) and MIF-substrate in the presence and absence of a test compound; detecting tautomerization of the MIF- substrate CYTOKINE PHARMASCIENCES, INC. 2003-06-05 US disclosed
US-6420188-B1 KITS FOR USE IN MONITORING CYTOKINE-MEDIATED TOXICITY, SHOCK, INFLAMMATION, GRAFT-VERSUS-HOST DISEASE, AND AUTOIMMUNE DISEASES THE PICOWER INSTITUTE FOR MEDICAL RESEARCH 2002-07-16 US disclosed
EP-0821551-A4 SCREENING ASSAY FOR THE IDENTIFICATION OF INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR PICOWER INST MED RES (US) 2000-07-19 EP disclosed
EP-0821551-A1 SCREENING ASSAY FOR THE IDENTIFICATION OF INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) 1998-02-04 EP disclosed
WO-1997029635-A1 SCREENING ASSAY FOR THE IDENTIFICATION OF INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) 1997-08-21 WO disclosed
US-4087520-A Lowering blood pressure with new L-3-(3,4-dihydroxyphenyl)-2-methyl-alanine peptides BOEHRINGER MANNHEIM GMBH (DT) 1978-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030105014-A1 Preparing reaction mixture of macrophage migration inhibitory factor(MIF) and MIF-substrate in the presence and absence of a test compound; detecting tautomerization of the MIF- substrate MIF, DDT, COMT HSD17B10 421/4885KDM4E 3305/4885MAPT 601/4885
US-12427200-B2 Compositions and methods for the treatment of viral infections FCGR3B, ALB, FCGR1A HSD17B10 4645/4885KDM4E 4753/4885MAPT 2394/4885
US-20260108618-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, FCGR1A, FCGR2A HSD17B10 4780/4885KDM4E 1225/4885MAPT 1974/4885
US-12569565-B2 Compositions and methods for the treatment of viral infections ALB, FCGR3B, FCGR1A HSD17B10 4784/4885KDM4E 1470/4885MAPT 2428/4885
US-20260000781-A1 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF FCGR2A, FCGR1A, FCGR3B HSD17B10 2909/4885KDM4E 1204/4885MAPT 4879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.