SCHEMBL1485978

SCHEMBL1485978

COc1ccc(Nc2ccc3c(O)cc(S(=O)(=O)O)cc3c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 3/20 0.59
CASP6 P55212 3/20 0.59
NSD2 O96028 3/20 0.59
DUSP3 P51452 2/20 0.59
PTPN5 P54829 2/20 0.59
PTPN11 Q06124 2/20 0.59
CASP7 P55210 1/20 0.59
SNCA P37840 2/20 0.55
CTDSP1 Q9GZU7 1/20 0.50
NT5E P21589 2/20 0.46
KDM4E B2RXH2 3/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
MAPT P10636 2/20 0.45
GAA P10253 1/20 0.45
THRB P10828 1/20 0.45
MAPK1 P28482 1/20 0.45
RECQL P46063 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29495139 1.00 PRMT1 (0.59) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL8604070 0.91 CASP6 (0.72) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL9236771 0.87 PRMT1 (0.74) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL30213847 0.87 PRMT1 (0.74) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL9722951 0.86 PRMT1 (0.68) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL10455386 0.86 SNCA (0.72) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL28987911 0.86 PRMT1 (0.52) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL9270614 0.85 SNCA (0.71) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL28685686 0.84 CA1 (0.55) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL29445517 0.83 CASP6 (0.82) PRMT1CASP6NSD2DUSP3PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0260561-B1 PROCESS FOR DYEING LEATHER WITH DYESTUFF MIXTURES BAYER AG (DE) 1993-03-17 EP claimed
EP-0260561-A2 Process for dyeing leather with dyestuff mixtures BAYER AG (DE) 1988-03-23 EP claimed
US-4101542-A USING HYDRAZINE OR SALTS OF DITHIONOUS ACID OR HYDROXYMETHANE SULFINIC ACID BAYER AKTIENGESELLSCHAFT (DE) 1978-07-18 US claimed
CN-116261924-A Polarizing element, polarizing plate, and display device provided with same 日本化药株式会社 2023-06-13 CN disclosed
CN-116097135-A Polarizing element, polarizing plate, and display device provided with same 日本化药株式会社 2023-05-09 CN disclosed
CN-116018381-A Polarizing film, polarizing plate and liquid crystal display device containing azo compound or salt thereof 日本化药株式会社 2023-04-25 CN disclosed
CN-108699346-B Azo compound or salt thereof, and polarizing film containing azo compound or salt thereof 日本化药株式会社 2021-06-29 CN disclosed
CN-108700692-B Polarizing component, polarizing plate using same and display device 日本化药株式会社 2021-03-16 CN disclosed
CN-111205671-A Azo compound or salt thereof, and polarizing film containing azo compound or salt thereof 日本化药株式会社 2020-05-29 CN disclosed
EP-2674461-B1 AZO COMPOUND, DYE-BASED POLARIZING FILM, AND POLARIZING PLATE NIPPON KAYAKU KK (JP) 2019-03-27 EP disclosed
US-20190048194-A1 Azo Compound Or Salt Thereof, And Polarizing Film Containing Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2019-02-14 US disclosed
EP-0384893-B1 Process for the preparation of asymmetrical 1,2-metal complex dyestuffs CIBA GEIGY AG (CH) 1994-09-07 EP disclosed
US-5229502-A PREPARATION OF 1:2 CHROMIUM COMPLEXES ONE SULFO SUBSTITUTED AND ONE SULFONAMIDO OR THE LIKE SUBSTITUTED AZO DYES CIBA-GEIGY CORPORATION (US) 1993-07-20 US disclosed
EP-0260561-B1 PROCESS FOR DYEING LEATHER WITH DYESTUFF MIXTURES BAYER AG (DE) 1993-03-17 EP disclosed
EP-0260557-B1 ASYMMETRIC 1:2 METAL COMPLEX DYESTUFS BAYER AG (DE) 1991-11-27 EP disclosed
EP-0384893-A1 Process for the preparation of asymmetrical 1,2-metal complex dyestuffs CIBA-GEIGY AG (CH) 1990-08-29 EP disclosed
EP-0066230-B1 1:2-ASYMMETRIC DYESTUFFS OF CHROMIUM BAYER AG (DE) 1986-03-05 EP disclosed
EP-0066230-A1 1:2-asymmetric dyestuffs of chromium BAYER AG (DE) 1982-12-08 EP disclosed
US-4101542-A USING HYDRAZINE OR SALTS OF DITHIONOUS ACID OR HYDROXYMETHANE SULFINIC ACID BAYER AKTIENGESELLSCHAFT (DE) 1978-07-18 US disclosed
US-3948879-A Phenylazonaphtholsulfonic acids having a substituted anilino group in the 6-position of the naphthalane ring SANDOZ LTD. (CH) 1976-04-06 US disclosed