SCHEMBL28685686

SCHEMBL28685686

COc1ccc(CNc2ccc3c(O)cc(S(=O)(=O)O)cc3c2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.55
CA2 P00918 3/20 0.55
CA12 O43570 2/20 0.55
CA9 Q16790 1/20 0.55
PRMT1 Q99873 1/20 0.53
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
MAPT P10636 3/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
LMNA P02545 1/20 0.49
EGLN2 Q96KS0 2/20 0.47
CASP6 P55212 3/20 0.47
NSD2 O96028 1/20 0.47
DUSP3 P51452 1/20 0.47
PTPN5 P54829 1/20 0.47
PTPN11 Q06124 1/20 0.47
CTDSP1 Q9GZU7 1/20 0.46
FFAR1 O14842 1/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28691759 0.87 PRMT1 (0.56) CA1CA2CA12CA9PRMT1
SCHEMBL28708886 0.84 PRMT1 (0.56) CA1CA2CA12CA9PRMT1
SCHEMBL29495139 0.84 PRMT1 (0.59) CA1CA2PRMT1NPC1RAB9A
SCHEMBL1485978 0.84 PRMT1 (0.59) CA1CA2PRMT1NPC1RAB9A
SCHEMBL28987914 0.84 PRMT1 (0.59) CA1CA2CA12CA9PRMT1
SCHEMBL7625817 0.79 PRMT1 (0.65) PRMT1CASP6NSD2DUSP3PTPN5
SCHEMBL28709255 0.77 PRMT1 (0.53) CA1CA2CA12CA9PRMT1
SCHEMBL11048362 0.76 PRMT1 (0.52) PRMT1NPC1RAB9AMAPTL3MBTL1
SCHEMBL28987911 0.76 PRMT1 (0.52) CA1CA2CA12CA9PRMT1
SCHEMBL1373255 0.76 PRMT1 (0.65) PRMT1CASP6NSD2DUSP3PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114008143-B Azo compound, polarizing film containing the same, and polarizing plate 日本化药株式会社 2024-05-14 CN disclosed
CN-114008143-A Azo compound, polarizing film containing the same, and polarizing plate 日本化药株式会社 2022-02-01 CN disclosed