SCHEMBL1486049

SCHEMBL1486049

CCCCCCC(N)C(N)(N)N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.50
SPHK1 Q9NYA1 2/20 0.46
CYP2D6 P10635 2/20 0.43
LMNA P02545 2/20 0.43
TP53 P04637 2/20 0.43
LAP3 P28838 2/20 0.43
PLA2G1B P04054 1/20 0.43
PLA2G2A P14555 1/20 0.43
GMNN O75496 1/20 0.43
POLB P06746 1/20 0.43
THPO P40225 1/20 0.43
MTOR P42345 1/20 0.43
BLM P54132 1/20 0.43
KDM4E B2RXH2 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPT P10636 1/20 0.43
CETP P11597 1/20 0.43
HTT P42858 1/20 0.43
UBE2N P61088 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23358953 1.00 OPRM1 (0.50) OPRM1SPHK1CYP2D6LMNATP53
SCHEMBL23358986 1.00 OPRM1 (0.50) OPRM1SPHK1CYP2D6LMNATP53
SCHEMBL23359008 1.00 OPRM1 (0.50) OPRM1SPHK1CYP2D6LMNATP53
SCHEMBL23358928 1.00 OPRM1 (0.50) OPRM1SPHK1CYP2D6LMNATP53
SCHEMBL3678135 0.97 OPRM1 (0.52) OPRM1SPHK1CYP2D6LMNATP53
SCHEMBL3676611 0.90 OPRM1 (0.42) OPRM1SPHK1CYP2D6LMNATP53
SCHEMBL6060496 0.83 OPRM1 (0.48) OPRM1SPHK1CYP2D6LMNATP53
SCHEMBL29153555 0.83 OPRM1 (0.48) OPRM1SPHK1CYP2D6LMNATP53
SCHEMBL14663498 0.83 OPRM1 (0.48) OPRM1SPHK1CYP2D6LMNATP53
SCHEMBL28372119 0.83 OPRM1 (0.48) OPRM1SPHK1CYP2D6LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11492710-B2 Trifunctional amine based corrosion inhibitor compositions ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2022-11-08 US claimed
US-20010006976-A1 Process for preparing azacycloalkanoylaminothiazoles BRISTOL-MYERS SQUIBB COMPANY 2001-07-05 US claimed
JP-57011018-A None JP disclosed
JP-7133404-A None JP disclosed
US-20250043168-A1 DRILLING FLUID ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2025-02-06 US disclosed
CN-116406412-A Drilling fluid 奥升德功能材料运营有限公司 2023-07-07 CN disclosed
US-11492710-B2 Trifunctional amine based corrosion inhibitor compositions ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2022-11-08 US disclosed
US-20220154061-A1 DRILLING FLUID ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2022-05-19 US disclosed
WO-2022103735-A1 DRILLING FLUID ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2022-05-19 WO disclosed
WO-2021101795-A1 TRIFUNCTIONAL AMINE BASED CORROSION INHIBITOR COMPOSITIONS ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2021-05-27 WO disclosed
US-20210147984-A1 TRIFUNCTIONAL AMINE BASED CORROSION INHIBITOR COMPOSITIONS ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2021-05-20 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed
US-6559314-B2 Reacting hexamethylenetetramine compound with cysteamine or its salts to produce thiazolidine PROBIODRUG AG (DE) 2003-05-06 US disclosed
US-6007972-A Photographic fixing composition containing an oxadiazolethione and method of rapid photographic processing EASTMAN KODAK COMPANY (US) 1999-12-28 US disclosed
EP-0761404-A1 Tire curing bladder with improved release characteristics THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-03-12 EP disclosed
US-5580513-A CROSSLINKED ELASTOMER; BLEND OF OLEFIN POLYMER AND CORN OIL THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-12-03 US disclosed
JP-H07133404-A MOLDING MATERIAL OF PHENOLIC RESIN TOAGOSEI CO LTD 1995-05-23 JP disclosed
US-5407290-A Connecting joint for electric furnace electrodes SOCIETE DES ELECTRODES ET (FR) 1995-04-18 US disclosed
JP-S5711018-A MANUFACTURE OF PHENOLIC RESIN MOLDING MATERIAL MATSUSHITA ELECTRIC WORKS LTD 1982-01-20 JP disclosed
EP-0019215-A1 Process for preparation of denatured polyaddition products from residues of distillation of isocyanates and biomasses and their use as reactive fillers as nutritious matter for plants and as binder in the production of panels or shaped pieces BAYER AG (DE) 1980-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010006976-A1 Process for preparing azacycloalkanoylaminothiazoles CDK9, CDK4, CDK6 OPRM1 1735/4885SPHK1 4683/4885CYP2D6 399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.