SCHEMBL14860640

SCHEMBL14860640

COc1ccccc1C=N[C@@H](C)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.56
MAPT P10636 5/20 0.56
KDM4E B2RXH2 4/20 0.56
HPGD P15428 3/20 0.56
GAA P10253 3/20 0.56
HSD17B10 Q99714 2/20 0.56
USP2 O75604 1/20 0.56
POLB P06746 1/20 0.56
ALOX15 P16050 1/20 0.56
ALOX12 P18054 1/20 0.56
RECQL P46063 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
GRIN2D O15399 2/20 0.47
GRIN3B O60391 2/20 0.47
GRIN1 Q05586 2/20 0.47
GRIN2A Q12879 2/20 0.47
GRIN2B Q13224 2/20 0.47
GRIN2C Q14957 2/20 0.47
GRIN3A Q8TCU5 2/20 0.47
MEN1 O00255 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14860639 1.00 ALDH1A1 (0.56) ALDH1A1MAPTKDM4EHPGDGAA
SCHEMBL27974852 1.00 ALDH1A1 (0.56) ALDH1A1MAPTKDM4EHPGDGAA
SCHEMBL14860069 1.00 ALDH1A1 (0.56) ALDH1A1MAPTKDM4EHPGDGAA
SCHEMBL14860070 1.00 ALDH1A1 (0.56) ALDH1A1MAPTKDM4EHPGDGAA
SCHEMBL9089342 0.86 MAPT (0.69) ALDH1A1MAPTKDM4EHPGDGAA
SCHEMBL9089348 0.86 MAPT (0.69) ALDH1A1MAPTKDM4EHPGDGAA
SCHEMBL1492111 0.85 GRIN2D (0.49) ALDH1A1MAPTKDM4EHPGDGAA
SCHEMBL1492113 0.85 GRIN2D (0.49) ALDH1A1MAPTKDM4EHPGDGAA
SCHEMBL6862696 0.82 GRIN2D (0.53) ALDH1A1MAPTKDM4EHPGDGAA
SCHEMBL6442988 0.78 GAA (0.43) ALDH1A1MAPTKDM4EHPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102892505-B Chiral heterogeneous catalyst for asymmetric nitroaldol reaction COUNCIL SCIENT IND RES 2015-02-11 CN claimed
US-8557726-B2 Chiral heterogeneous catalyst for assymmetric nitroaldol reaction COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-10-15 US claimed
US-20130096333-A1 Chiral Heterogeneous Catalyst for Assymmetric Nitroaldol Reaction COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-04-18 US claimed
CN-102892505-A Chiral heterogeneous catalyst for asymmetric nitroaldol reaction COUNCIL SCIENT IND RES 2013-01-23 CN claimed
CN-102892505-B Chiral heterogeneous catalyst for asymmetric nitroaldol reaction COUNCIL SCIENT IND RES 2015-02-11 CN disclosed
US-8557726-B2 Chiral heterogeneous catalyst for assymmetric nitroaldol reaction COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-10-15 US disclosed
US-20130096333-A1 Chiral Heterogeneous Catalyst for Assymmetric Nitroaldol Reaction COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-04-18 US disclosed
CN-102892505-A Chiral heterogeneous catalyst for asymmetric nitroaldol reaction COUNCIL SCIENT IND RES 2013-01-23 CN disclosed