Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 4/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | RECQL | P46063 | 2/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9089342 | 1.00 | MAPT (0.69) | MAPTKDM4EGAAPOLBRECQL | |
| SCHEMBL9087730 | 0.89 | MAPT (0.59) | MAPTKDM4EGAAPOLBRECQL | |
| SCHEMBL9089147 | 0.89 | MAPT (0.59) | MAPTKDM4EGAAPOLBRECQL | |
| SCHEMBL9087725 | 0.89 | MAPT (0.59) | MAPTKDM4EGAAPOLBRECQL | |
| SCHEMBL9089143 | 0.89 | MAPT (0.59) | MAPTKDM4EGAAPOLBRECQL | |
| SCHEMBL14860640 | 0.86 | ALDH1A1 (0.56) | MAPTKDM4EGAAPOLBRECQL | |
| SCHEMBL14860069 | 0.86 | ALDH1A1 (0.56) | MAPTKDM4EGAAPOLBRECQL | |
| SCHEMBL14860070 | 0.86 | ALDH1A1 (0.56) | MAPTKDM4EGAAPOLBRECQL | |
| SCHEMBL27974852 | 0.86 | ALDH1A1 (0.56) | MAPTKDM4EGAAPOLBRECQL | |
| SCHEMBL14860639 | 0.86 | ALDH1A1 (0.56) | MAPTKDM4EGAAPOLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510519-A | OPTICAL RESOLUTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0508307-B1 | Optically active secondary amine compound; process for producing optically active secondary amine compound and process for producing optically active carboxylic acid by using said compound | SUMITOMO CHEMICAL CO (JP) | 1995-11-29 | — | — | EP | disclosed |
| US-5298660-A | Compound containing an assymetrical carbon atom | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-03-29 | — | — | US | disclosed |
| EP-0508307-A2 | Optically active secondary amine compound; process for producing optically active secondary amine compound and process for producing optically active carboxylic acid by using said compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-10-14 | — | — | EP | disclosed |