Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.62 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.47 |
| ▸ | PI4KA | P42356 | 2/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31621268 | 1.00 | ASH1L (0.62) | ASH1LPIK3CAPI4KAPI4KBALDH1A1 | |
| SCHEMBL2624081 | 0.83 | ALDH1A1 (0.50) | ASH1LALDH1A1MAPTHSD17B10KDM4E | |
| SCHEMBL189244 | 0.82 | ASH1L (0.59) | ASH1LPIK3CAPI4KAPI4KBALDH1A1 | |
| SCHEMBL29013240 | 0.79 | ASH1L (0.49) | ASH1LALDH1A1MAPTLIMK1HSD17B10 | |
| SCHEMBL30312029 | 0.79 | ASH1L (0.49) | ASH1LALDH1A1MAPTLIMK1HSD17B10 | |
| SCHEMBL30128071 | 0.79 | PIK3CA (0.45) | ASH1LPIK3CAPI4KAPI4KBALDH1A1 | |
| SCHEMBL22027627 | 0.79 | PIK3CA (0.45) | ASH1LPIK3CAPI4KAPI4KBALDH1A1 | |
| SCHEMBL30311933 | 0.79 | ASH1L (0.59) | ASH1LALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL30311887 | 0.79 | ASH1L (0.59) | ASH1LKDM4EIKBKBADORA2AADORA1 | |
| SCHEMBL29013266 | 0.79 | ASH1L (0.59) | ASH1LKDM4EIKBKBADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850263-A | 2, 7-disubstituted benzothiazole compound and application thereof | 浙江工业大学 | 2023-03-28 | — | — | CN | disclosed |
| EP-2766359-A2 | HETEROCYCLIC COMPOUNDS AND USE THEREOF AS MODULATORS OF TYPE III RECEPTOR TYROSINE KINASES | Ambit Biosciences Corporation (US) | 2014-08-20 | — | — | EP | disclosed |
| WO-2013056070-A2 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2013-04-18 | — | — | WO | disclosed |