Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245734 | 0.83 | MAOB (0.74) | MAOBCYP19A1KDM4EHSD17B10ADORA3 | |
| SCHEMBL11245731 | 0.83 | MAOB (0.74) | MAOBCYP19A1KDM4EHSD17B10ADORA3 | |
| SCHEMBL14861591 | 0.81 | MAOB (0.67) | MAOBCYP19A1KDM4EHSD17B10ADORA3 | |
| SCHEMBL403523 | 0.81 | MAOB (0.65) | MAOBCYP19A1KDM4EHSD17B10ADORA3 | |
| SCHEMBL32498549 | 0.81 | MAOB (0.65) | MAOBCYP19A1KDM4EHSD17B10ADORA3 | |
| SCHEMBL25194272 | 0.80 | KDM4E (0.47) | MAOBCYP19A1KDM4EHSD17B10ADORA3 | |
| Water SCHEMBL6439945 | 0.79 | MAOB (0.62) | MAOBCYP19A1KDM4EHSD17B10ADORA3 | |
| SCHEMBL28176992 | 0.77 | HTR1A (0.48) | MAOBCYP19A1KDM4EHSD17B10ADORA3 | |
| SCHEMBL17449876 | 0.76 | TTR (0.65) | MAOBCYP19A1KDM4EHSD17B10KMT2A | |
| SCHEMBL20928443 | 0.75 | FFAR1 (0.40) | MAOBRAB9AKMT2ANPC1ALOX15B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766120-A1 | METHOD FOR CATALYTIC HETEROAROMATIC HYDROGENATION | Westfälische Wilhelms-Universität Münster (DE) | 2014-08-20 | — | — | EP | disclosed |
| WO-2013053796-A1 | METHOD FOR CATALYTIC HETEROAROMATIC HYDROGENATION | Westfälische Wilhelms Universität Münster (DE) | 2013-04-18 | — | — | WO | disclosed |
| WO-2013053796-A1 | METHOD FOR CATALYTIC HETEROAROMATIC HYDROGENATION | Westfälische Wilhelms Universität Münster (DE) | 2013-04-18 | — | — | WO | disclosed |