Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14864110 | 0.98 | FOLH1 (0.38) | FOLH1SIRT2OPRK1TPSAB1POLB | |
| SCHEMBL14980045 | 0.92 | FOLH1 (0.37) | FOLH1SIRT2OPRK1TPSAB1POLB | |
| SCHEMBL14980086 | 0.90 | FOLH1 (0.38) | FOLH1SIRT2OPRK1TPSAB1POLB | |
| SCHEMBL277487 | 0.89 | SIRT2 (0.40) | FOLH1SIRT2TPSAB1HDAC4 | |
| SCHEMBL15474215 | 0.86 | TPSAB1 (0.36) | FOLH1SIRT2TPSAB1POLBHSD17B10 | |
| SCHEMBL12692605 | 0.86 | FOLH1 (0.38) | FOLH1SIRT2OPRK1HDAC3HDAC4 | |
| SCHEMBL14864098 | 0.85 | SIRT2 (0.35) | FOLH1SIRT2TPSAB1POLBHSD17B10 | |
| SCHEMBL14980081 | 0.84 | SIRT2 (0.34) | FOLH1SIRT2TPSAB1POLBHSD17B10 | |
| SCHEMBL17812998 | 0.83 | FOLH1 (0.33) | FOLH1SIRT2OPRK1TPSAB1 | |
| SCHEMBL277717 | 0.82 | SIRT2 (0.35) | FOLH1SIRT2OPRK1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420068-B2 | Polymer-based compositions and conjugates of antimicrobial agents | NEKTAR THERAPEUTICS (US) | 2013-04-16 | — | — | US | disclosed |