Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17813015 | 0.84 | ACE (0.31) | SIRT2 | |
| SCHEMBL14864110 | 0.84 | FOLH1 (0.38) | FOLH1OPRK1SIRT2TPSAB1 | |
| SCHEMBL14980086 | 0.83 | FOLH1 (0.38) | FOLH1OPRK1SIRT2TPSAB1 | |
| SCHEMBL14864111 | 0.83 | FOLH1 (0.37) | FOLH1OPRK1SIRT2TPSAB1 | |
| SCHEMBL14980045 | 0.82 | FOLH1 (0.37) | FOLH1OPRK1SIRT2TPSAB1 | |
| SCHEMBL18724456 | 0.81 | ALDH1A1 (0.31) | — | |
| SCHEMBL17812997 | 0.81 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL12509458 | 0.81 | — | — | |
| SCHEMBL17812993 | 0.80 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL15474215 | 0.79 | TPSAB1 (0.36) | FOLH1SIRT2TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9763995-B2 | Polymer conjugates of protegrin peptides | NEKTAR THERAPEUTICS (US) | 2017-09-19 | — | — | US | disclosed |
| US-20160158311-A1 | POLYMER CONJUGATES OF PROTEGRIN PEPTIDES | NEKTAR THERAPEUTICS | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158311-A1 | POLYMER CONJUGATES OF PROTEGRIN PEPTIDES | PSMG3, PSMB11, UBQLN1 | FOLH1 1296/4885OPRK1 2760/4885SIRT2 3088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.