Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 3/20 | 0.40 |
| ▸ | RORA | P35398 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | RORB | Q92753 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13232927 | 1.00 | LMNA (0.42) | LMNAATMMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL13233022 | 0.96 | LMNA (0.39) | LMNAATMMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL13233019 | 0.96 | LMNA (0.39) | LMNAATMMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL13232925 | 0.94 | KDM4E (0.43) | LMNAATMMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL13232931 | 0.94 | KDM4E (0.43) | LMNAATMMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL25752315 | 0.93 | KDM4E (0.53) | LMNAATMMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL13232922 | 0.92 | KDM4E (0.39) | LMNAATMMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL14464662 | 0.90 | KDM4E (0.42) | LMNAATMMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL13232932 | 0.90 | RORC (0.41) | LMNAATMMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL13077287 | 0.89 | KDM4E (0.46) | LMNAATMMAPK1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420234-B2 | Organic electroluminescent device | UDC IRELAND LIMITED (IE) | 2013-04-16 | — | — | US | disclosed |
| US-8420234-B2 | Organic electroluminescent device | UDC IRELAND LIMITED (IE) | 2013-04-16 | — | — | US | disclosed |