SCHEMBL1486437

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1486497	0.89	HRH3 (0.42)	HRH3DYRK1ACYP3A4GRM4NMT1
	SCHEMBL1486436	0.87	TLR7 (0.45)	HRH3DYRK1ACYP3A4GRM4NMT1
	SCHEMBL1486507	0.86	TLR7 (0.47)	HRH3DYRK1ACYP3A4GRM4NMT1
	SCHEMBL1486628	0.85	ACACB (0.34)	HRH3DYRK1APIK3CDPIK3CAMTOR
	SCHEMBL4239447	0.84	NPC1 (0.49)	HRH3DYRK1ACYP3A4GRM4MEN1
	SCHEMBL1486540	0.82	TLR7 (0.55)	HRH3DYRK1ACYP3A4TLR8
	SCHEMBL1486565	0.80	TLR7 (0.46)	PIK3CDPIK3CAMTOR
	SCHEMBL6724014	0.80	SMN1; SMN2 (0.47)	PIK3CDPIK3CAMTORMEN1KMT2A
	SCHEMBL1486585	0.79	NMT1 (0.42)	HRH3NMT1NPC1RAB9APDGFRB
	SCHEMBL1486575	0.78	NMT1 (0.45)	HRH3NMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.