Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | TYMP | P19971 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13183610 | 0.80 | MTNR1A (0.39) | MTNR1ATAAR1CNR2GPR55ELANE | |
| SCHEMBL15114873 | 0.77 | RAB9A (0.47) | MTNR1ATAAR1ALDH1A1HPGDGPR55 | |
| SCHEMBL20773262 | 0.73 | EGFR (0.40) | EGFRTYMPTAAR1ARADRA2A | |
| SCHEMBL2090458 | 0.72 | TAAR1 (0.56) | TYMPTAAR1ARP2RX7ALDH1A1 | |
| SCHEMBL29477327 | 0.72 | TAAR1 (0.56) | TYMPTAAR1ARP2RX7ALDH1A1 | |
| SCHEMBL16061555 | 0.70 | POLB (0.54) | HTR2CHTR2BTAAR1ALDH1A1HPGD | |
| SCHEMBL11200954 | 0.70 | TAAR1 (0.54) | TYMPTAAR1ARP2RX7ALDH1A1 | |
| SCHEMBL29772212 | 0.70 | TAAR1 (0.54) | TYMPTAAR1ARP2RX7ALDH1A1 | |
| SCHEMBL16900005 | 0.69 | HTR2C (0.50) | HTR2CHTR2BTAAR1ARUSP2 | |
| SCHEMBL21163713 | 0.68 | PDK2 (0.40) | HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420686-B2 | Linked diimidazole antivirals | ENANTA PHARMACEUTICALS, INC. (US) | 2013-04-16 | — | — | US | disclosed |