Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13183517 | 0.83 | — | — | |
| SCHEMBL31563944 | 0.75 | PTPN1 (0.31) | — | |
| SCHEMBL13021599 | 0.74 | HPGD (0.44) | LMNAHPGDTSHRSMN1; SMN2 | |
| SCHEMBL23840301 | 0.72 | HPGD (0.44) | LMNAHPGDTSHRSMN1; SMN2 | |
| SCHEMBL31564036 | 0.71 | — | — | |
| SCHEMBL18723893 | 0.66 | LIMK1 (0.35) | — | |
| SCHEMBL18723612 | 0.66 | WNT3A (0.32) | HPGD | |
| SCHEMBL6421619 | 0.66 | PNMT (0.44) | — | |
| SCHEMBL4009115 | 0.65 | — | — | |
| SCHEMBL17815188 | 0.65 | KCNQ2 (0.40) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420686-B2 | Linked diimidazole antivirals | ENANTA PHARMACEUTICALS, INC. (US) | 2013-04-16 | — | — | US | disclosed |