Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PRNP | P04156 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30890023 | 0.85 | KDM4E (0.73) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9449433 | 0.85 | KDM4E (0.73) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3107611 | 0.83 | PRNP (0.71) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL24721602 | 0.80 | MAPT (0.49) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6703458 | 0.80 | KDM4E (0.55) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL17296934 | 0.79 | POLB (0.70) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL20094576 | 0.77 | KDM4E (0.70) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL29198788 | 0.76 | KDM4E (0.66) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3091494 | 0.76 | KDM4E (0.66) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2816058 | 0.75 | ALDH1A1 (0.67) | MAPTKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2581451-A1 | Compounds for inhibiting mammalian s-nitrosoglutathione reductase | Indiana University Research and Technology Corporation (US) | 2013-04-17 | — | — | EP | disclosed |