Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 0.55 |
| ▸ | WNT3A | P56704 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8172220 | 0.80 | QDPR (0.62) | QDPR | |
| SCHEMBL29435634 | 0.80 | QDPR (0.50) | QDPRGABRA5 | |
| SCHEMBL22583246 | 0.80 | QDPR (0.50) | QDPRGABRA5 | |
| SCHEMBL22583321 | 0.79 | QDPR (0.52) | QDPRGABRA5 | |
| Hydrochloric Acid SCHEMBL22583432 | 0.77 | QDPR (0.51) | QDPRGABRA5 | |
| SCHEMBL17664585 | 0.76 | QDPR (0.58) | QDPR | |
| SCHEMBL7369176 | 0.76 | QDPR (0.72) | QDPR | |
| SCHEMBL19107631 | 0.76 | QDPR (0.64) | QDPR | |
| SCHEMBL8264178 | 0.76 | QDPR (0.59) | QDPR | |
| SCHEMBL15345162 | 0.75 | QDPR (0.45) | QDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994004-B9 | 1,4-DISUBSTITUTED 3-CYANO-PYRIDONE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2-RECEPTORS | JANSSEN PHARMACEUTICALS INC (US) | 2013-04-17 | — | — | EP | disclosed |