Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62801 | 0.77 | KMT2A (0.50) | ALDH1A1KMT2AMEN1OPRM1CHRM2 | |
| SCHEMBL3441323 | 0.73 | CRHBP (0.39) | ALDH1A1SMN1; SMN2LMNATSHRKMT2A | |
| SCHEMBL21023414 | 0.73 | CACNA2D1 (0.68) | CACNA1HCACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL10125744 | 0.73 | DPP4 (0.37) | SMN1; SMN2LMNAADRA2ACYP2D6HTR2A | |
| SCHEMBL19052338 | 0.72 | SLC6A2 (0.34) | TSHRSLC6A3GAA | |
| SCHEMBL13715496 | 0.69 | — | — | |
| SCHEMBL20792846 | 0.69 | SMN1; SMN2 (0.35) | SMN1; SMN2LMNATSHRKMT2AMEN1 | |
| SCHEMBL22210648 | 0.69 | — | — | |
| SCHEMBL10264737 | 0.69 | KMT2A (0.33) | ALDH1A1KMT2AMEN1OPRM1CHRM2 | |
| SCHEMBL12649195 | 0.68 | ACHE (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2058302-B1 | METHOD FOR PRODUCING PHENOXYPYRIDINE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2013-04-17 | — | — | EP | disclosed |