Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 8/20 | 0.39 |
| ▸ | CES1 | P23141 | 5/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18823290 | 0.82 | PAOX (0.50) | PAOXMEN1KMT2AALDH1A1PLG | |
| SCHEMBL18768794 | 0.79 | PAOX (0.46) | PAOXMEN1KMT2AALDH1A1PLG | |
| SCHEMBL13893493 | 0.79 | PAOX (0.56) | PAOXMEN1KMT2AALDH1A1PLG | |
| SCHEMBL13893494 | 0.79 | PAOX (0.56) | PAOXMEN1KMT2AALDH1A1PLG | |
| SCHEMBL18350804 | 0.79 | PAOX (0.56) | PAOXMEN1KMT2AALDH1A1PLG | |
| SCHEMBL13089653 | 0.79 | PAOX (0.56) | PAOXMEN1KMT2AALDH1A1PLG | |
| SCHEMBL19771702 | 0.77 | PAOX (0.54) | PAOXMEN1KMT2AALDH1A1PLG | |
| SCHEMBL25083812 | 0.76 | CES1 (0.39) | MEN1KMT2AALDH1A1THRBHDAC6 | |
| SCHEMBL16187339 | 0.76 | PAOX (0.52) | PAOXMEN1KMT2AALDH1A1PLG | |
| SCHEMBL7192719 | 0.76 | FAAH (0.53) | MEN1KMT2AALDH1A1ALOX15FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2194068-B1 | CYCLODEXTRIN COMPOUND MODIFIED WITH FOLIC ACID, PROCESS FOR PRODUCTION THEREOF, DRUG DELIVERY AGENT FOR TARGETING DRUG DELIVERY SYSTEM, PHARMACEUTICAL COMPOSITION, AND IMAGING AGENT | NANODEX INC (JP) | 2013-04-17 | — | — | EP | disclosed |