SCHEMBL13089653

SCHEMBL13089653

CC(C)(C)C(=O)CCCCCN

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 4/20 0.56
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.52
LMNA P02545 2/20 0.52
THRB P10828 2/20 0.52
ALDH1A1 P00352 1/20 0.52
PLG P00747 1/20 0.52
ALOX15 P16050 1/20 0.52
SLC6A2 P23975 1/20 0.52
RECQL P46063 1/20 0.52
SLC6A3 Q01959 1/20 0.52
CYP2D6 P10635 1/20 0.48
NFKB1 P19838 1/20 0.48
BLM P54132 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
HDAC6 Q9UBN7 2/20 0.46
FAAH O00519 7/20 0.40
CES1 P23141 5/20 0.40
CES2 O00748 2/20 0.40
CYP1A2 P05177 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18350804 1.00 PAOX (0.56) PAOXKMT2AMEN1LMNATHRB
SCHEMBL13893493 1.00 PAOX (0.56) PAOXKMT2AMEN1LMNATHRB
SCHEMBL13893494 1.00 PAOX (0.56) PAOXKMT2AMEN1LMNATHRB
SCHEMBL16187339 0.98 PAOX (0.52) PAOXKMT2AMEN1LMNATHRB
SCHEMBL10110819 0.90 CYP1A2 (0.48) PAOXKMT2AMEN1LMNATHRB
SCHEMBL16722811 0.87 FAAH (0.48) KMT2AMEN1LMNAALDH1A1NFKB1
SCHEMBL16640758 0.87 FAAH (0.48) KMT2AMEN1LMNAALDH1A1NFKB1
SCHEMBL19163900 0.87 FAAH (0.48) KMT2AMEN1LMNAALDH1A1NFKB1
SCHEMBL13661862 0.87 FAAH (0.48) KMT2AMEN1LMNAALDH1A1NFKB1
SCHEMBL12247043 0.87 FAAH (0.48) KMT2AMEN1LMNAALDH1A1NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037355-B2 Triterpene saponin analogues ADJUVANCE TECHNOLOGIES, INC. (US) 2024-07-16 US disclosed
US-20230263886-A1 VACCINES, VACCINE PRIMING, AND ANTIGEN DOSE SPARING ADJUVANCE TECHNOLOGIES, INC. 2023-08-24 US disclosed
US-20230219991-A1 TRITERPENE SAPONIN ANALOGUES ADJUVANCE TECHNOLOGIES, INC. (US) 2023-07-13 US disclosed
US-20230183326-A1 PROTEIN-POLYMER-DRUG CONJUGATES ASANA BIOSCIENCES, LLC 2023-06-15 US disclosed
US-20230183326-A1 PROTEIN-POLYMER-DRUG CONJUGATES ASANA BIOSCIENCES, LLC 2023-06-15 US disclosed
US-20230174985-A1 MODIFIED PEPTIDE NUCLEIC ACID COMPOSITIONS NEUBASE THERAPEUTICS, INC. 2023-06-08 US disclosed
US-20230128815-A1 ADJUVANT COMPOUNDS, SALT FORMS, AND FORMULATIONS ADJUVANCE TECH INC (US) 2023-04-27 US disclosed
US-20230043447-A1 PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES MERSANA THERAPEUTICS, INC. 2023-02-09 US disclosed
US-20230021500-A1 CYSTEINE ENGINEERED ANTIBODY-DRUG CONJUGATES WITH PEPTIDE-CONTAINING LINKERS MERSANA THERAPEUTICS, INC. 2023-01-26 US disclosed
US-20220409721-A1 VARICELLA ZOSTER ADJUVANCE TECHNOLOGIES, INC. (US) 2022-12-29 US disclosed
US-8821850-B2 Protein-polymer-drug conjugates MERSANA THERAPEUTICS, INC. (US) 2014-09-02 US disclosed
US-8815226-B2 Protein-polymer-drug conjugates MERSANA THERAPEUTICS, INC. (US) 2014-08-26 US disclosed
US-20140134127-A1 Protein-Polymer-Drug Conjugates MERSANA THERAPEUTICS, INC. (US) 2014-05-15 US disclosed
US-20140017265-A1 Terminally Modified Polymers and Conjugates Thereof MERSANA THERAPEUTICS, INC. 2014-01-16 US disclosed
US-20130101546-A1 Protein-Polymer-Drug Conjugates MERSANA THERAPEUTICS, INC. (US) 2013-04-25 US disclosed
US-20100267757-A1 AMINOTHIAZOLES AND THEIR USES NOVARTIS AG (CH) 2010-10-21 US disclosed
US-20090280106-A1 Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use BAYER PHARMACEUTICALS CORPORATION (US) 2009-11-12 US disclosed
US-20090280106-A1 Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use BAYER PHARMACEUTICALS CORPORATION (US) 2009-11-12 US disclosed
US-20090105122-A1 Selective neuropeptide y2 receptor agonists BAYER PHARMACEUTICALS CORPORATION (US) 2009-04-23 US disclosed
US-20090105122-A1 Selective neuropeptide y2 receptor agonists BAYER PHARMACEUTICALS CORPORATION (US) 2009-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267757-A1 AMINOTHIAZOLES AND THEIR USES ABAT, AADAT, GOT2 PAOX 212/4885KMT2A 1982/4885MEN1 3821/4885
US-20230219991-A1 TRITERPENE SAPONIN ANALOGUES LSS, NFATC1, PGGT1B PAOX 161/4885KMT2A 4265/4885MEN1 4051/4885
US-20140134127-A1 Protein-Polymer-Drug Conjugates PBRM1, CLTB, BRAP PAOX 856/4885KMT2A 2203/4885MEN1 4707/4885
US-20230128815-A1 ADJUVANT COMPOUNDS, SALT FORMS, AND FORMULATIONS MYD88, TLR7, NFATC1 PAOX 204/4885KMT2A 2665/4885MEN1 2573/4885
US-20090280106-A1 Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use ADCYAP1R1, VIPR2, ADCY2 PAOX 1044/4885KMT2A 1853/4885MEN1 285/4885
US-20230183326-A1 PROTEIN-POLYMER-DRUG CONJUGATES PBRM1, STAMBP, TSPO PAOX 614/4885KMT2A 1732/4885MEN1 2537/4885
US-20140017265-A1 Terminally Modified Polymers and Conjugates Thereof MALT1, ALG1, PRMT3 PAOX 2650/4885KMT2A 1139/4885MEN1 1055/4885
US-20230021500-A1 CYSTEINE ENGINEERED ANTIBODY-DRUG CONJUGATES WITH PEPTIDE-CONTAINING LINKERS LNPEP, DNPEP, QPCT PAOX 4757/4885KMT2A 2425/4885MEN1 1894/4885
US-20230174985-A1 MODIFIED PEPTIDE NUCLEIC ACID COMPOSITIONS TARDBP, SARNP, SNRPE PAOX 3744/4885KMT2A 2835/4885MEN1 2427/4885
US-20230043447-A1 PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES CD2BP2, DNPEP, LNPEP PAOX 4622/4885KMT2A 3687/4885MEN1 1711/4885
US-20090105122-A1 Selective neuropeptide y2 receptor agonists NPY2R, NPY1R, NPY4R PAOX 891/4885KMT2A 1579/4885MEN1 877/4885
US-20220409721-A1 VARICELLA ZOSTER IFNG, HLA-DRB1, CXCL10 PAOX 2893/4885KMT2A 4327/4885MEN1 4020/4885
US-20230263886-A1 VACCINES, VACCINE PRIMING, AND ANTIGEN DOSE SPARING MYD88, CD14, DDOST PAOX 1132/4885KMT2A 3509/4885MEN1 3138/4885
US-12037355-B2 Triterpene saponin analogues LSS, NFATC1, PGGT1B PAOX 161/4885KMT2A 4265/4885MEN1 4051/4885
US-20130101546-A1 Protein-Polymer-Drug Conjugates PBRM1, CLTB, BRAP PAOX 852/4885KMT2A 1978/4885MEN1 4727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.