Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6263872 | 0.97 | TSHR (0.41) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL14865445 | 0.88 | TSHR (0.38) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL27648890 | 0.88 | TSHR (0.38) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL18806310 | 0.85 | DNM1 (0.55) | TSHRMEN1KMT2ANAAADNM1 | |
| SCHEMBL27394427 | 0.85 | TSHR (0.48) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL19288688 | 0.85 | TSHR (0.48) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL25005784 | 0.83 | NAAA (0.37) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL24759713 | 0.83 | NAAA (0.37) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL24754282 | 0.81 | TSHR (0.40) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL11760325 | 0.81 | TSHR (0.44) | TSHRTHRBMEN1KMT2ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2581377-B1 | HYDROSILANE DERIVATIVE, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING SILICON-CONTAINING THIN FILM | TOSOH CORP (JP) | 2015-07-29 | — | — | EP | disclosed |
| EP-2581377-A1 | HYDROSILANE DERIVATIVE, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING SILICON-CONTAINING THIN FILM | Tosoh Corporation (JP) | 2013-04-17 | — | — | EP | disclosed |